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Hot information：
Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Jun 17,2016
Mutated Cilia Genes Shown to Lead to Scoliosis
    Researchers at Princeton University and the University of Toronto report that in zebrafish irregular fluid flow through the spinal column brought on by gene mutations is linked to a type of scoliosis that can affect humans during adolescence. Found in humans and zebrafish, these mutated genes damage the cilia that line the spinal canal andRead more
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Mutated Cilia Genes Shown to Lead to Scoliosis
Jun 16,2016
Fix to RNA Editing Glitch May Defuse Blast Crisis
    Few cancer mechanisms are as devastating as the generation of cancer stem cells, which arise in leukemia from white blood cell precursors. The mechanisms of this transition have been obscure, but the consequences are all too clear. Leukemia stem cells promote an aggressive, therapy-resistant form of disease called blast crisis.     The self-renewal of leukemia stemRead more
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Jun 16,2016
Scientists Unpack How Toxoplasma Infection Link to Neurodegenerative Disease
    A cold shudder would radiate down most anyone's spine when thinking about a parasitic organism residing within the cells of their brain. Yet, roughly 15–30% of the U.S population and up to a staggering 80% of the populations in France and Brazil are infected with the protozoan parasite Toxoplasma gondii.       Toxoplasma gondii, a protozoanRead more
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Jun 15,2016
Bladder Cancer Response to Therapy Revealed by Whole Exome Sequencing
    Scientists at the University of Colorado Cancer Center say they used next-generation sequencing technologies to perform the most detailed DNA-based analysis to date of 25 commonly used bladder cancer cell lines. The work allowed the team to match patient tumors with their closest genetic cell line match and demonstrated genetic alterations that may make cellsRead more
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Bladder Cancer Response to Therapy Revealed by Whole Exome Sequencing
Jun 15,2016
Rapid Retrieval of Infectious Pathogens from Clinical Samples
    Pinpointing the type of bacteria that are at the root of an infection in clinical samples removed from living tissues, such as blood, urine or joint fluids, to quickly identify the best anti-microbial therapy still poses a formidable challenge. The standard method of culturing can take days to reveal pathogens, and they often fail toRead more
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Jun 14,2016
Swapping Sick for Healthy Brain Cells Slows Huntington Disease
    Researchers have successfully reduced the symptoms and slowed the progression of Huntington's disease in mice using healthy human brain cells. The investigators implanted animals with human glial cells derived from stem cells. One of the roles of glia is to tend to the health of neurons, and the results from this new study reveal thatRead more
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Swapping Sick for Healthy Brain Cells Slows Huntington Disease
Jun 14,2016
Mitochondria Shown to Help Repair Damaged Neurons
    Scientists at the National Institute of Neurological Disorders and Stroke have discovered that boosting the transport of mitochondria along neuronal axons enhances the ability of mouse nerve cells to repair themselves after injury. The study ("Facilitation of Axon Regeneration by Enhancing Mitochondrial Transport and Rescuing Energy Deficits”), which appears in The Journal of Cell Biology,Read more
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Mitochondria Shown to Help Repair Damaged Neurons
Jun 13,2016
Copper is Key in Burning Fat
    A freshly minted study indicates that copper could help restore a natural way to burn fat. Copper, it turns out, can alter the balance of metabolic accounts through its influence on a biochemical signaling pathway.
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Jun 13,2016
PD L1 Mutations ID Patients Resistant to Immunotherapy
    Cancer immunotherapy has ignited a firestorm of new drug compounds that target novel tumor markers that activate patients' immune system to destroy various cancer cell types. These therapies have provided remarkable success; however, they are expensive to produce and administer, with a percentage of patients showing little to no therapeutic efficacy. Now, scientists at KyotoRead more
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PD L1 Mutations ID Patients Resistant to Immunotherapy
Jun 10,2016
Human Protein Found to Block Zika Infection
    Scientists have finally figured out what Zika virus does to the human body, and it explains why its effects can be so devastating, but infections can go for months without detection.     Researchers at the University of Massachusetts Medical School (UMMS) say they have found that interferon-induced protein 3 (IFITM3) can dramatically reduce the ability ofRead more
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Human Protein Found to Block Zika Infection
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