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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Jun 24,2016
Improving Healing by Targeting Weak Electric Fields in Wounds
    People with diabetes often suffer from wounds that are slow to heal and can lead to ulcers, gangrene, and amputation. Now, an international team led by Min Zhao, M.D., Ph.D., professor of ophthalmology and of dermatology at the University of California, Davis, has shown that, in animal models of diabetes, slow healing is associated withRead more
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Jun 23,2016
Iridium Implant Makes for a Bionic Metalloenzyme
We can rebuild it. We have the technology. We can make it better than it was. With apologies to Oscar Goldman, the "it” here isn't an expensive cyborg, but rather an iridium-substituted myoglobin, a metalloprotein that is ordinarily built around iron. With a noble metal at its heart rather than the common transition metal, myoglobinRead more
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Iridium Implant Makes for a Bionic Metalloenzyme
Jun 23,2016
Impact of Antibiotic Treatment on Infant Gut Microbiome Revealed
    A comprehensive analysis of changes in the intestinal microbial population during the first three years of life has revealed some of the impacts of factors such as mode of birth — vaginal versus cesarean section — and antibiotic exposure, including the effects of multiple antibiotic treatments. In the June 15 issue of Science Translational Medicine,Read more
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Jun 22,2016
Pituitary Tissue Grown from Human Stem Cells Releases Hormones in Rats
Researchers at Sloan Kettering Institute for Cancer Research have successfully used human stem cells to generate functional pituitary tissue that secretes hormones important for the body's stress response as well as for its growth and reproductive functions. When transplanted into rats with hypopituitarism–a disease linked to dwarfism and premature aging in humans–the lab-grown pituitary cellsRead more
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Pituitary Tissue Grown from Human Stem Cells Releases Hormones in Rats
Jun 22,2016
Visualizing T Cells in Action
    Scientists from the Salk Institute say they have imaged how vital receptors on the surface of T-cells bundle together when activated to fight an invading pathogen. The study ("Superresolution Imaging Reveals Nanometer- and Micrometer-Scale Spatial Distributions of T-Cell Receptors in Lymph Nodes”), published in PNAS, and reportedly the first to visualize this process in lymphRead more
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Visualizing T Cells in Action
Jun 21,2016
Nanotechnology Tool Allows Detailed Study of Proteins in Living Cells
    Scientists from Massachusetts General Hospital (MGH) and the Rowland Institute at Harvard University have used a specialized nanoprobe developed by the Harvard/Rowland investigators to measure levels of key proteins directly within living, cultured cells. As described in Nano Letters ("Direct Tracking of Amyloid and Tau Dynamics in Neuroblastoma Cells Using Nanoplasmonic Fiber Tip Probes”), the investigatorsRead more
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Nanotechnology Tool Allows Detailed Study of Proteins in Living Cells
Jun 21,2016
Virus Hacker Commits CRISPR Heist to Protect Itself
    Phage viruses have evolved to infect bacteria, breaking into their genomes to take over their replication machinery. Sometimes, two different viruses may go for the same victim, competing over who will dominate the newly created virus factory bacterium.     However now, researchers from the University of British Columbia (UBC) have recently described their findings surrounding aRead more
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Jun 20,2016
Experimental Antibiotic Treats Deadly MRSA Infection
    The thought of an aggressive bacterial infection that is resistant to the arsenal of antimicrobial compounds is frightening, to say the least. Yet, this is currently an issue for a handful of microbial pathogens, and there is an ever looming threat of more bacteria emerging to become multidrug resistant.       However, now a new experimentalRead more
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Experimental Antibiotic Treats Deadly MRSA Infection
Jun 20,2016
Protecting against Liver Cancer by Removing the Feed Trough
    Scientists at Ecole Polytechnique Federale De Lausanne (EPFL) say they have found a way to starve liver cancer cells by blocking a protein that is required for glutamine breakdown, while leaving normal cells intact. The discovery opens new ways to treat liver cancer.       Primary liver cancer is the second leading cause of cancer-related deaths worldwide,Read more
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Protecting against Liver Cancer by Removing the Feed Trough
Jun 17,2016
New Tool Brings Personalized Medicine Closer
    Researchers and physicians are increasingly learning that medical interventions can be more successful when they are tailored to the particular profile of the individual patient. Yet, defining that profile has proven tough, as it involves information on an individual's genome, proteins, fats, and variety of other biomolecules that constitute the individual’s tissue makeup. And so far,Read more
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