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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Jul 15,2016
The Fountain of Youth Molecule from Pomegranate Discovered
    Superfoods are unfortunately a bit of a misnomer, as they won't actually give you any superpowers; but over the years they have been touted as providing extreme nutritional and health benefits. For instance, pomegranates have been marketed as supplying consumers with superior antioxidant levels and antiaging properties. Yet up until now, scientific proof has beenRead more
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The Fountain of Youth Molecule from Pomegranate Discovered
Jul 14,2016
Healthy Aging More Doubtful if Nuclear and Mitochondrial Genomes Clash
    Mitochondrial DNA (mtDNA) doesn't have to be pathogenic or intrinsically flawed to impair health. It just has to be a poor match with nuclear DNA.  Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC), have uncovered how the combination and interaction between our two genomes, the nuclear and the mitochondrial, triggers a cellular adaptation thatRead more
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Healthy Aging More Doubtful if Nuclear and Mitochondrial Genomes Clash
Jul 14,2016
Big Data Shows Cancer Cell Lines Reflect Patient Tumor Mutations
    New research shows that patient-derived cancer cell lines harbor most of the same genetic changes found in patients' tumors and could be used to learn how tumors are likely to respond to new drugs. The findings ("A Landscape of Pharmacogenomic Interactions in Cancer”), published in Cell, should help increase the success rate for developing new, more personalizedRead more
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Big Data Shows Cancer Cell Lines Reflect Patient Tumor Mutations
Jul 13,2016
Role Found for microRNA Molecule in Development of Schizophrenia
    Researchers report that microRNA (miRNA) could make the difference between a healthy adult brain and one that’s prone to disorders including schizophrenia. Specifically, a team at the Salk Institute discovered that miR-19 guides the placement of new neurons in the adult brain, and the molecule is disrupted in cells from patients with schizophrenia.     Their study (“FunctionalRead more
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Jul 13,2016
Liquid Biopsy Predicts Colon Cancer Recurrence
One of the most exciting applications of precision medicine is the minimally to noninvasive technique of isolating tumor DNA from biofluids for diagnostic purposes—the aptly named liquid biopsy. This screening tool incorporates the power and speed of next-generation sequencing (NGS) to either diagnose disease or track the progression of a disease throughout a patient's lifeRead more
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Liquid Biopsy Predicts Colon Cancer Recurrence
Jul 12,2016
Programmable RNA Vaccines Are Effective in Mice Against Ebola and Flu
The insertion of a rapid response force requires the right vehicle, however small the deployment. At the nanoscale, the right vehicle might be a dendrimer platform, one that can encapsulate messenger RNA (mRNA) vaccines and transport them across cell membranes as readily as viral particles. MIT engineers have developed a new type of easily customizableRead more
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Programmable RNA Vaccines Are Effective in Mice Against Ebola and Flu
Jul 12,2016
Parkinson Disease Could Be Detected Through a Urine Test
    Detection of Parkinson's disease (PD) traditionally has never been an exact science, as many diagnoses rely on the classification of various symptoms and behavioral anomalies. However, several other neurological disorders present with very similar symptomology as PD but have entirely different clinical outcomes and treatment regimens. In recent years, scientists have searched for specific DNARead more
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Parkinson Disease Could Be Detected Through a Urine Test
Jul 11,2016
Promise for Pancreatic Cancer from New Immunotherapy Results
Pancreatic cancer is a particularly troubling diagnosis, as most of the tumors are extremely aggressive and often unresponsive to traditional chemotherapy regimens. Moreover, in recent years immunotherapy has proven effective in treating various types of cancer, especially melanoma and carcinomas of the lung, yet so far, pancreatic tumors have remained impervious to immune-based therapies.     HoweverRead more
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Promise for Pancreatic Cancer from New Immunotherapy Results
Jul 11,2016
New Target Discovered for Combatting Muscle Aging or Disease
As we age, the function and regenerative abilities of skeletal muscles deteriorate, which means it is difficult for the elderly to recover from injury or surgery. Now, researchers at the Carnegie Institution of Washington report that β1-integrin is crucial for muscle regeneration. Their findings ("Targeting β1-Integrin Signaling Enhances Regeneration in Aged and Dystrophic Muscle inRead more
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New Target Discovered for Combatting Muscle Aging or Disease
Jul 08,2016
How Genes Guide Our Response to Pathogens
    Have you ever wondered why some healthy people cannot defend themselves well against bacteria or fungi while others may get away with mild symptoms? Researchers believe that genetic factors that control immune cell response to pathogens could partly explain this varied response.     A study ("Inter-Individual Variability and Genetic Influences on Cytokine Responses to Bacteria andRead more
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How Genes Guide Our Response to Pathogens