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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Aug 04,2016
Single Protein Protects against Neurodegenerative Diseases
    A new study led by researchers at the University of Glasgow has identified how cells protect themselves against misfolded and aggregated proteins known to be the cause of neurodegenerative diseases such as Alzheimer's, Parkinson's, and Huntington's diseases. The researchers are hopeful that the results from this new study will provide needed insight into the biochemicalRead more
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Single Protein Protects against Neurodegenerative Diseases
Aug 04,2016
Preclinical Trials Services in Drug Development
Medicilon has good preclinical trials services in drug development. Medicilon offers GLP and Non-GLP preclinical testing for the pharmaceutical and medical-device industries. We're tremendously proud of our environmentally controlled animal facilities, surgery suites and necropsy labs. However, we understand they're only a starting point for your preclinical studies. Key Preclinical Services Include: Preclinical Research ServiceRead more
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Preclinical Trials Services in Drug Development
Aug 03,2016
Halting Translation of Cancer Promoting Proteins
    Most cancer drugs are designed to halt cell growth, the hallmark of cancer, and one popular target is the pathway that controls the production of a cell's thousands of proteins.     A familiar initiation factor, eukaryotic initiation factor 3 subunit d (eIF3d), has been found to harbor an unfamiliar feature—a sort of hidden compartment. What's more,Read more
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Halting Translation of Cancer Promoting Proteins
Aug 03,2016
Recruiting KRAS to Attack Lung Cancer
    Scientists at the University of Texas Southwestern Medical Center say they have identified a new way to target lung cancer through the KRAS (Kirsten rat sarcoma viral oncogene homolog) gene, one of the most commonly mutated genes in human cancer and one researchers have so far had difficulty targeting successfully.     Investigators studying the underlying biology of KRAS inRead more
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Aug 02,2016
Gene Therapy Improves Metabolic Liver Disease Outcome
    Scientists at the Mayo Clinic are testing a new approach to correct metabolic liver disorders without a whole-organ transplant. Their findings ("Curative Ex Vivo Liver-Directed Gene Therapy in a Pig Model of Hereditary Tyrosinemia Type 1”) appear in Science Translational Medicine.     The medical research study tested gene therapy in pigs suffering from hereditary tyrosinemia typeRead more
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Gene Therapy Improves Metabolic Liver Disease Outcome
Aug 02,2016
Genetic Factors Sculpt Cortical Patterns
    The ridges and valleys of the human cortex look sculpted—and in a sense, they are. In fact, these undulating shapes reflect the work of many tiny sculptors, genetic factors that work together to realize a developmental program that is remarkably consistent from individual to individual. These genetic factors remain mostly anonymous, but a new studyRead more
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Genetic Factors Sculpt Cortical Patterns
Aug 01,2016
Sniffing Out Alzheimer Disease
    Our nose helps us identify odors, from a cup of coffee to the smoke of a cigarette. As we age, an impaired sense of smell is normal, but completely losing our sense of smell could be a sign of brain damage.       What if it were possible to predict cognitive decline and detect the earlyRead more
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Sniffing Out Alzheimer Disease
Aug 01,2016
Patch Has Tumor Covered with Drug, Gene, and Light Therapy
It's an adhesive patch that is way more than a Band-Aid. And it's not just one of those medicated patches that are used to deliver nicotine, a contraceptive, or a pain killer. This patch is a triple-threat aimed straight at cancer. Once it is slapped on a tumor, it delivers a combination of drug, gene,Read more
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Patch Has Tumor Covered with Drug, Gene, and Light Therapy
Jul 29,2016
Male Hormone Reverses Cell Aging
Telomerase, an enzyme naturally found in the human organism, is the closest of all known substances to a "cellular elixir of youth.”  The impact of the telomerase enzyme's discovery cannot be overstated, as its importance to cell biology was recognized in 2009 with the awarding of the Nobel Prize in Physiology or Medicine.
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Male Hormone Reverses Cell Aging
Jul 29,2016
Old Malaria Drug May Have New Role Fighting Cancer
An old cancer drug can not only kill cancer cells, but also works to change how certain cancer cells function, weakening those cells so they can be killed by other drugs, a veterinary researcher has discovered. An off-patent antimalarial, atovaquone, has been utilized to boost cancer-killing capabilities of radiation. Atovaquone came into existence evaluated likeRead more
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