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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Aug 17,2016
Medicilon's Cell Based Bioassay Development Services
Cell Based Bioassay Development Services Cell Based Bioassays, are designed to establish the potency and stability of a drug substance or product and are important in establishing safety and efficacy profiles for biopharmaceuticals.  Medicilon provides in-vitro assay development and compound screening services.  We offer access to cell based screening assay services from Reaction Biology. CellularRead more
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Medicilon's Cell Based Bioassay Development Services
Aug 16,2016
How Bacteria in the Mouth Make Colon Cancer Worse
Of cancers that strike both men and women, colorectal cancer (CRC) is the No. 2 killer in the US, reports the CDC, claiming more than 50,000 lives in 2013.  Evidence emerges almost daily in support of the microbiome's influence on a variety of body systems and disease states. Yet, can it be true that various.
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How Bacteria in the Mouth Make Colon Cancer Worse
Aug 16,2016
Generated Neuronal Cells May Serve as Brain Disease Models
    Scientists at Duke University say they used the CRISPR technique to convert cells isolated from mouse connective tissue directly into neuronal cells.       In 2006, Shinya Yamanaka, Ph.D., a professor at the Institute for Frontier Medical Sciences at Kyoto University at the time, discovered how to revert adult connective tissue cells (fibroblasts) back into immatureRead more
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Generated Neuronal Cells May Serve as Brain Disease Models
Aug 15,2016
Dog Fear and Aggression Genes Related to Human Anxiety
    Anxiety disorders are the most common type of mental illness in the United States. And while much is understood about the biochemistry of anxiety, little is known about the genetic variation associated with it.       Some dogs snarl and snap at anyone—familiar people, even their owners. Other dogs display aggression more selectively, directing it towardRead more
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Dog Fear and Aggression Genes Related to Human Anxiety
Aug 15,2016
Epigenetic Activity Imaged in Human Brain for First Time
    Scientists at the Martinos Center for Biomedical Imaging at Massachusetts General Hospital (MGH) say they have developed a novel positron emission tomography (PET) radiotracer that reveals epigenetic activity within the human brain. In their report (“Insights into Neuroepigenetics through Human Histone Deacetylase PET Imaging”), published in Science Translational Medicine, the investigators report how their radiochemical, called Martinostat, shows the expression levelsRead more
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Aug 12,2016
Killer T Cells See Cancer Driving Mutations before Turning Blind Eye
Early in tumor development, well before a tumor becomes clinically recognizable, so-called driver mutations steer cancerous cells down aberrant developmental paths, changing not only the behavior but also the appearance of the cells. And yet these altered cells would seem to escape the notice of the immune system's killer T cells, which are supposed toRead more
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Aug 12,2016
Breakthrough in Combating Malaria with Odor Baited Trap for Mosquitoes
    In the war against malaria, there are numerous fronts on which the battle to prevent disease transmission take place. Vector (mosquito) control is an area that has seen its share of limited success over the years, mainly through the use of insecticides such as DDT. However, resistance to many insecticides has forced investigators to searchRead more
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Aug 11,2016
Single Compound Is Triple Threat among Neglected Tropical Diseases
    Parasitic infections from protozoan species affect hundreds of millions of individuals annually, mounting a massive death toll globally. Yet, among these diseases, there are a few that are isolated to much smaller regions and populations, causing them to be often overlooked during drug development.       Now scientists at the Wellcome Trust, Novartis Research Foundation (GNF),Read more
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Single Compound Is Triple Threat among Neglected Tropical Diseases
Aug 11,2016
Stem Cells of Worms and Humans Are Similar Than Expected
    Stem cells are cellular all-rounders and can differentiate into any tissue. They hold great potential for regenerative medicine, which is why they are subject to intense study. Planarians, small free-living flatworms, are especially interesting for researchers due to their remarkable ability to regenerate any lost body part through their many stem cells.     When stem cellsRead more
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Aug 11,2016
JCI: Scientists discover potential ways to treat early type 2 diabetes
Recently, in a research report published in the International Journal of Clinical Investigation, researchers from the Sanford Burnham Prebys Institute of Medical Discovery have identified a potential drug target that inhibits the occurrence of type 2 diabetes. The results show that , Blocking the glucose receptors in the cells of muscle may improve the body'sRead more
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