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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Aug 29,2016
Cutting Morrbid RNA Shortens Immune Cell Lifespan
    Gene transcription can be as capricious as the Fates, who personified destiny and reserved the right to cut the thread of life, but it might yet be persuaded to be as balanced as Justice, a sister to the Fates who was dedicated to keeping the order and setting limits to any action. Depending on howRead more
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Cutting Morrbid RNA Shortens Immune Cell Lifespan
Aug 26,2016
Autism Risk Linked to Banned Chemicals, Not Vaccines
    The search for the underlying causes of autism has sparked heated debates and an unfortunate glut of bad science. Most notable was the thoroughly debunked Wakefield study that erroneously tied vaccinations to the rise in autism rates. Scientists have been trying actively to repair some of the lasting damage that has befallen not only theRead more
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Autism Risk Linked to Banned Chemicals, Not Vaccines
Aug 26,2016
Put Molecules on the Rack to Extract Structural Secrets
    Enhanced interrogation is coming to molecular structure studies in the form of MOFs, or metal-organic frameworks. These sturdy crystalline networks hold uncooperative molecules still while they are doused with X-rays. Sounds harsh. But resorting to MOFs doesn't stretch, distort, or break molecules. It merely keeps them still for analysis by means of X-ray crystallography orRead more
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Put Molecules on the Rack to Extract Structural Secrets
Aug 26,2016
Medicilon's Preclinical Pharmacokinetic Study Services
Pharmacokinetics is the study of the way the body deals with the absorption, distribution, metabolism, and excretion of drugs under investigation expressed in mathematical terms. The effects and the duration of action of the drug are also taken into account. With over 12 years of experience of operating a GLP and non-GLP compliant laboratory, MedicilonRead more
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Medicilon's Preclinical Pharmacokinetic Study Services
Aug 26,2016
FDA grants priority review qualification for ovarian cancer drug candidate Rucaparib
The FDA recently granted Clovis Oncology a priority review. The company is seeking approval for its experimental drug Rucaparib for the treatment of ovarian cancer. Once the news was released, the company’s stock price soared as much as 38%. This PARP inhibitor is being evaluated for advanced ovarian cancer in patients with BRCA mutations (includingRead more
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Aug 25,2016
Hispanic Paradox Explained through Epigenetics
    A new paper reports that Latinos age at a slower rate than other ethnic groups. The study ("An Epigenetic Clock Analysis of Race/Ethnicity, Sex, and Coronary Heart Disease”), published in Genome Biology, may one day lead to novel approaches that help slow the aging process for everyone, according to lead author Steve Horvath, Ph.D., professor of human genetics atRead more
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Hispanic Paradox Explained through Epigenetics
Aug 25,2016
Researchers Discover New Inflammatory Disease
    NIH researchers report the discovery of a rare and sometimes lethal inflammatory disease – otulipenia – that primarily affects young children. They have also identified anti-inflammatory treatments that ease some of the patients' symptoms: fever, skin rashes, diarrhea, joint pain, and overall failure to grow or thrive.     Otulipenia is caused by the malfunction of OTULIN,Read more
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Researchers Discover New Inflammatory Disease
Aug 24,2016
Eye Color Determines Risk for Cancer
    Clinical and epidemiological data have always pointed to eye cancer being more common among those individuals with light eye coloration and fair skin—however, the genetic mechanisms underlying disease development have been largely unknown. Now new research from investigators at The Ohio State University (OSU) and New York University (NYU) sheds light on specific inherited geneticRead more
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Eye Color Determines Risk for Cancer
Aug 24,2016
Mending of Chromosomal Split Ends Seen in Real Time
A pair of techniques—CRISPR gene editing and single-molecule microscopy—have been put together to subject telomere repair to a new level of scrutiny, one that not only zooms in on single proteins, but also tracks the proteins over time. The proteins, fluorescently labeled versions of telomerase, were observed displaying a kind of probing behavior, rapidly stickingRead more
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Aug 24,2016
Medicilon's Drug ADME/PK Assays Services
Medicilon's pharmacokinetics department offers the clients a broad spectrum of high quality of services in the areas of in vitro ADME, in vivo pharmacokinetics and bioanalysis services, ranging from small molecules to large molecules, such as protein and antibody. The animal species involved in our services are non-human primate, canine, mice, rat, rabbit and etc.Read more
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Medicilon's Drug ADME/PK Assays Services