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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Oct 06,2016
Facing the Ethical Challenges of Genome Editing
    As humans we constantly stand upon a precipice, trying to straddle what is good for our species and what is ethical as a species. We are constantly faced with the question "just because we can do it, should we?” Nowhere has this become more apparent in recent years than within the field of molecular biology.Read more
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Oct 05,2016
Attacking Drug Resistant Bacteria by Targeting the BAM Complex
    Scientists report that improved understanding of the way in which hundreds of different types of disease-causing bacteria operate could help pave the way to tackling their effects.      University of Leeds researchers led by Sheena Radford, Ph.D., and Neil Ranson, Ph.D., have uncovered new information about the operation of a protein complex called BAM, the beta-barrelRead more
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Oct 05,2016
Nobel Prize in Medicine Awarded for Autophagy Discoveries
    Yoshinori Ohsumi, Ph.D., a microbiologist who discovered and elucidated mechanisms underlying the degradation and recycling of cellular components, was named sole winner of the 2016 Nobel Prize in Physiology or Medicine.     Dr. Ohsumi, a professor at the Tokyo Institute of Technology, was honored for discoveries that shed light on the importance of autophagy in manyRead more
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Nobel Prize in Medicine Awarded for Autophagy Discoveries
Oct 04,2016
Vaccinations Lead to Measles Free America
    An encouraging announcement was made recently at the 55th Directing Council of the Pan American Health Organization/World Health Organization (PAHO/WHO), which declared the Region of the Americas the first in the world to have eliminated measles. Measles is now the fifth vaccine-preventable disease to be eliminated from the Americas, after the regional eradication of smallpoxRead more
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Oct 04,2016
Synthetic Lethal Gene Pairs Reveal Life Sustaining Genome Networks
Like human resource consultants looking to reduce headcount without hurting productivity, or even destroying the company, molecular geneticists have been downsizing genomes, paying especial attention to which gene losses affect the life of the cell and which do not. For example, molecular geneticists based at the University of Toronto recently tried deleting two genes atRead more
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Synthetic Lethal Gene Pairs Reveal Life Sustaining Genome Networks
Oct 03,2016
Autism and Kidney Issues Linked Through Deleted Gene
    A collaboration of investigators from the Developmental Biology Institute of Marseille and the University of Manchester have just published data that identifies the link between kidney issues and autism spectrum disorder (ASD) in children. The researchers are optimistic that their findings will have a sweeping impact on how physicians working on both conditions administer testsRead more
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Oct 03,2016
Fungus Makes Mosquitoes More Susceptible to Malaria
    We often don't think of what insects, such as mosquitoes, are exposed to in their environment or how it affects their primitive immune systems. A mosquito's sheer annoyance factor is more than enough to overshadow any sympathy one might generate toward any other species that is negatively affected by external factors. Yet, when these deleteriousRead more
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Sep 30,2016
Boosting Cancer Immunotherapy with Iron Nanoparticles
    Iron nanoparticles can activate the immune system to attack cancer cells, according to a study led by researchers at the Stanford University School of Medicine. The nanoparticles, which are commercially available as the injectable iron supplement ferumoxytol, are approved by the FDA to treat iron deficiency anemia.     The mouse study found that ferumoxytol prompts immune cellsRead more
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Boosting Cancer Immunotherapy with Iron Nanoparticles
Sep 30,2016
Endurance Training Causes Widespread Genetic Changes
    The physiological impact of regular endurance training can be visualized over time and is often used to prevent cardiovascular disease, diabetes, obesity and other such conditions. However, how these changes occur at the molecular level and their impact on a genomic scale lack complete resolution. Now, investigators from the Karolinska Institutet report on their recentRead more
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Sep 30,2016
Computer Aided Drug Design Services
Over the past many years, Medicilon's drug discovery landscape has changed dramatically. Many pharmaceutical companies have shifted their research efforts from enzyme targets to programs based on more complex phenotypic screens. These screens create rich datasets, which often lack the resolution found in traditional enzyme assays. Even in cases where drug targets are known, teamsRead more
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Computer Aided Drug Design Services