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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021

Medicilon Assist – New progress in the field of NASH! Hepadin's HPD001 is about to start clinical trials in the U.S.

Recently, HPD001, an original innovative drug independently developed by Guangzhou Hapedin, will start clinical trials in the United States. The drug was approved by the FDA for clinical research last year, and the indication is non-alcoholic steatohepatitis (NASH).

Medicilon Assist – New progress in the field of NASH! Hepadin's HPD001 is about to start clinical trials in the U.S.

Medicilon Flow Cytometry Technology Platform

Flow Cytometry is a modern multi-parameter cell analysis technology that can detect single particles at high speed, accurately and objectively. At present, in the early stage of drug development, especially for anti-tumor drugs, complex cell analysis through flow multicolor detection technology can provide scientific researchers with maximum effective data. Flow cytometry technology has obvious advantagesRead more

Medicilon Flow Cytometry Technology Platform

Potassium ion channel, calcium ion channel, sodium ion channel

Ion channels are channels on the cell membrane that can regulate and transport specific ions through the cell membrane. They are usually composed of protein molecules, and often several transmembrane protein subunits form an ion channel. It is an important basis for maintaining the information transmission of the body's nervous system, the rhythmic beating ofRead more

Potassium ion channel, calcium ion channel, sodium ion channel

Preclinical Toxicological Safety Evaluation of Biological Drugs

Toxicology Safety Evaluation of Biological Drugs Biological drugs is one of the fastest-growing sub-sectors in the pharmaceutical industry in recent years. From the global drug sales rankings in the past few years, it can be seen that the proportion of biopharmaceuticals among the top 10 drugs sold has increased year by year. In 2017, seven of theseRead more

Preclinical Toxicological Safety Evaluation of Biological Drugs

What is pharmacokinetics?

In drug development, various parameters need to be established in preclinical trials before the drug is approved for preliminary testing in human subjects. Pharmacokinetics is an area of research that helps scientists understand how molecules behave in the body. Overview of Pharmacokinetics Pharmacokinetics, sometimes referred to as PK (Pharmacokinetic), is a branch of pharmacology thatRead more

What is pharmacokinetics?

What is IND in New Drug Research?

IND Full English name: Investigational New Drug The FDA new drug review process includes two processes: IND application for new drug clinical trial application and NDA application for new drug application. IND is for clinical trial application, and NDA is for new drug marketing application. Medicilon provide the IND filing for the preclinical services. MedicilonRead more

What is IND in New Drug Research?

How to do a good job of biological analysis of peptide drugs?

Since Robert Bruce Merrifield synthesized the first biologically active peptide in 1953, research on peptide drugs has developed rapidly, and research on peptide drugs targeting multiple receptors has even been carried out internationally. The maturity of peptide synthesis technology has further accelerated the development of peptide drugs and has become one of the international researchRead more

How to do a good job of biological analysis of peptide drugs?

Experimental Steps of Western Blotting Test

Western blot is a protein detection and analysis technique widely used in the fields of biology and medicine. It can be used to detect the expression level of specific proteins in tissue homogenates or cell extracts. Western blotting technology steps are mainly divided into two parts, namely SDS-polyacrylamide gel electrophoresis (SDS-PAGE) and immunoblotting. The BiologyRead more

Experimental Steps of Western Blotting Test

Do you know about western blotting?

IBT and LIA The Western blot detection technology currently used is not the original Western blot (IBT) but an optimized and improved method. western blotting Traditional Western Blotting (IBT): the protein is separated and purified by electrophoresis and transferred to a nitrocellulose membrane, and then autoimmune serum is used as a probe to react withRead more

Do you know about western blotting?

Western Blot Detection

The Biology Department of Shanghai Medicilon has extensive experience in the field of in vitro biology, through enzyme level determination, cell level determination, cell biology, biochemistry, in vitro isotope determination, stable cell line establishment, gene knockout, RNAi and MicroRNA Technology, etc., to provide a complete set of biological services. In cell biology research, sometimes itRead more

Western Blot Detection

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