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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Nov 23,2016
Novel Technique Pinpoints How APOL1 Gene Contributes to Kidney Disease
    Researchers from the Children’s National Health System research say they have discovered a novel process by which the APOL1 gene contributes to renal disease. They reported their finding (“APOL–G1 in Nephrocytes Induces Hypertrophy and Accelerates Cell Death”) in the Journal of the American Society of Nephrology.     Mutated versions of the APOL1 gene render people of African descent atRead more
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Nov 23,2016
Synthetic Proteins Click on DNA Repair, Give Snaps of Early Cancer
    Fleeting expressions and gestures can be more revealing than static poses, which is why candid snapshots are often valued more than formal portraits. Yet snapshots of cancer are few and far between. Cancer, in its earliest stages, is unusually camera-shy, biochemically speaking. When cancer originates in DNA repair mechanisms that turn awry, tell-tale DNA repairRead more
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Synthetic Proteins Click on DNA Repair, Give Snaps of Early Cancer
Nov 22,2016
Gene Editing Works in Nondividing Cells, Ameliorates Blindness
    Researchers have discovered a holy grail of gene editing — the ability to, for the first time, insert DNA at a target location into the non-dividing cells that make up the majority of adult organs and tissues. The technique, which the team showed was able to partially restore visual responses in blind rodents, will openRead more
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Nov 22,2016
Cancer Drug Discovery Gets Nutty
    "All things are poison, and nothing is without poison—only the dose makes a thing not a poison,” reads the familiar adage from the 15th century Swiss-German, physician, philosopher, and founder of toxicology, Paracelsus. Researchers have known for centuries that commonly toxic substances can also make useful tools when studying disease, and in some instances canRead more
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Nov 21,2016
Brain Signaling Circuit Finding May Lead to New Therapies for Neuro Disorders
    A specific signaling circuit in the brain is deeply involved in morotr activity, scientists from the Florida campus of The Scripps Research Institute (TSRI) have found.  Their new findings could have an impact on the development of therapies for a number of currently untreatable brain disorders such as Parkinson's and Huntington's diseases.         TheRead more
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Brain Signaling Circuit Finding May Lead to New Therapies for Neuro Disorders
Nov 21,2016
Novel Technique Detects Proteins Found to be Cancer Biomarkers
    An innovative technique to detect particular types of proteins that act as indicators for cancer and other diseases was recently developed by a biochemist at Purdue University.       Glycoproteins are formed when sugars attach to and modify a protein. In some cases, a combination of glycoproteins present in a sample of blood or urine couldRead more
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Novel Technique Detects Proteins Found to be Cancer Biomarkers
Nov 18,2016
Novel Machine-Learning Tool Opens Door to Improved Cancer Therapies
    Scientists have described about 1100 antimicrobial peptides (AMP) with diverse sequences that can permeate microbial membranes. Now researchers from the University of Illinois at Urbana-Champaign and UCLA report the development of a new machine learning approach to discover and design alpha-helical membrane-active peptides based on their physicochemical properties.     “In this work, we have trained aRead more
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Nov 18,2016
Human CRISPR Trials Could Become Sputnik 2.0
    It was the injection heard around the world. On October 28th, a team of scientists at Sichuan University in Chengdu, China, delivered the first cells that had been genetically altered using the revolutionary genome-editing technique called CRISPR (clustered regularly interspaced short palindromic repeats) into a human patient with aggressive lung cancer.  While it initially lookedRead more
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Nov 17,2016
Mosquitoes Could Carry Viral Triple Threat
    With autumn winding down across North America and the morning frost lingering longer into the day, it's difficult to think about those balmy summer nights where the world's deadliest animal silently buzzes around, looking for its next target to take its essential blood meal. Yet, much of the globe is starting its summer cyclesRead more
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Nov 17,2016
Marijuana-Like Drugs May Offer Addiction-Free Pain Relief
    As abuse of prescription opioids in the United States has reached epidemic proportions, researchers around the nation have been searching for other ways to offer people pain relief, ways that don’t bring such a risk of addiction.     Researchers from Indiana University took the stage at the annual meeting of the Society for Neuroscience in SanRead more
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