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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Dec 15,2016
HPLC Method Development Service
Chemical Analytical Center of Medicilon provides general analysis and purification services for the clients. Our experts have rich experience and proficient skills to solve problems, which are highly appreciated by clients. General Analytical Chemistry Services – NMR 1D、2D(H-NMR、C-NMR、P-NMR、F-NMR、HSQC、HMBC、COSY、NOESY, et al) – LC-MS Analysis – HPLC Analysis (including ELSD) – Chiral HPLC Analysis – General TestingRead more
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HPLC Method Development Service
Dec 15,2016
Breast Cancer Mortality Rates Declined Globally
    Breast cancer mortality rates continue to fall around the world, but there are disparities, particularly in South Korea and Latin America, according to a study presented recently at the San Antonio Breast Cancer Symposium (SABCS).     “Breast cancer is by far the primary cancer site in women and, worldwide, represents a quarter of all cancers inRead more
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Dec 15,2016
Scripps Florida Uses Precision Medicine Method to Tackle RNA Diseases
    Scientists on the Florida campus of The Scripps Research Institute (TSRI) have developed broad methods to design precision medicines against currently incurable diseases caused by RNA. In a study (“Precise Small Molecule Recognition of a Toxic CUG RNA Repeat Expansion”) published online ahead of press in Nature Chemical Biology, the team disclosed several approaches to overcome these hurdles.Read more
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Dec 14,2016
Novel Bladder Cancer Therapy Based on Arginine Deprivation Shows Promising Results
    Scientists from the University of California, San Diego (UCSD) report that more than 90% of all bladder cancers are deficient in argininosuccinate synthetase 1 (ASS1), an enzyme necessary for arginine synthesis, and patients with tumors having low ASS1 expression have shorter survival. Treatment with the arginine-degrading enzyme ADI-PEG 20 inhibited tumor growth in ASS1-deficient cells bothRead more
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Dec 14,2016
RNA Modification Helps Drosophila Straighten Up and Fly Right
    Absent a certain RNA modification, the flies folded their wings askew, lost their sense of direction, and wafted about listlessly—more listlessly than is ordinary. The RNA modification that the flies lacked is called m6A, which refers to the methylation of the nitrogen at position 6 of the adenosine base within messenger RNA (mRNA). The wobblyRead more
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RNA Modification Helps Drosophila Straighten Up and Fly Right
Dec 14,2016
LC-MS Analysis Service
LC/MS/MS Method Development & Validation Development, transfer, and optimization of methods for quantification of drugs in biological matrices Quick turnaround time to speed up the drug development process  Chemical Analytical Center of Medicilon provides general analysis and purification services for the clients. Our experts have rich experience and proficient skills to solve problems, which are highlyRead more
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LC-MS Analysis Service
Dec 13,2016
Medicilon’s Cell Invasion Assay
Cell invasion is cell migration through a physiological barrier in response to a chemoattractant, and this recapitulates cell movement within a physiological environment which is composed of extracellular matrix proteins. Here, the membranes are coated with a layer of extracellular matrix proteins, and the cells must traverse this barrier through a combination of protein degradationRead more
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Medicilon’s Cell Invasion Assay
Dec 13,2016
For Some Tumor Cells, Fat Greases the Skids for Metastasis
    Tumor cells that promote metastasis can be distinguished from tumor cells that do not, report scientists at the Institute for Research in Biomedicine (IRB Barcelona). According to these scientists, metastasis-inducing tumor cells have a particular taste for fat—very particular, in that they express high levels of the fatty acid receptor CD36 and lipid metabolism genes.Read more
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For Some Tumor Cells, Fat Greases the Skids for Metastasis
Dec 13,2016
An Anti-CRISPR for Gene Editing
    Researchers have discovered a way to program cells to inhibit CRISPR-Cas9 activity. “Anti-CRISPR” proteins had previously been isolated from viruses that infect bacteria, but now University of Toronto and University of Massachusetts Medical School scientists report three families of proteins that turn off CRISPR systems specifically used for gene editing. The work, “Naturally Occurring Off-SwitchesRead more
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Dec 12,2016
Medicilon’s Cell Viability Assay
Medicilon Cell Viability Assay offers a simple, rapid, reliable, sensitive, safe and cost-effective measurement of cell viability. Cell viability is a determination of living or dead cells, based on a total cell population. Cell viability assess healthy cells in a sample, with no distinction between dividing or quiescent cells. An increase in cell viability indicatesRead more
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Medicilon’s Cell Viability Assay