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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021

Analysis of the Characteristics of Aerosol and Preformulation Research

Aerosol is a dosage form of medicine. It is a dispersion system composed of fine liquid droplets or solid particles (dispersed inner phase) in air or mixed gas (dispersed outer phase). The dispersed ions are extremely small, and the diameter is from 1 to hundreds of nanometers. , Generally divided into high, medium and lowRead more

Analysis of the Characteristics of Aerosol and Preformulation Research

Application of Western Blot Analysis in Studying the Proliferation of NM23B Gene Cells

NM23 is a tumor metastasis suppressor gene, which has regulatory functions on cell proliferation, differentiation and ontogeny. At present, 10 subtypes of NM23 have been found, and the more thorough research is NM23A and NM23B. Western blot analysis shows that NM23B has hepatocyte proliferation effect on SD rats cultured in vitro. Western blot analysis, alsoRead more

Application of Western Blot Analysis in Studying the Proliferation of NM23B Gene Cells

Western blot analysis technique in detecting protein expression level

Lung cancer is one of the most harmful malignant tumors. To explore the pathogenesis of lung cancer and find new targets for anti-tumor therapy are the hotspots and difficulties in the current research on lung cancer treatment. Studies have found that aquaporin 4 (AQP4) is highly expressed in lung cancer cells, and knocking down AQP4Read more

Western blot analysis technique in detecting protein expression level

Factors Influencing the Dissolution of Solid Dosage Forms

In theory, in vivo drug testing is the most important and reliable basis for evaluating drugs. However, in the development of oral solid dosage forms, the method of measuring bioavailability is used to screen and evaluate each new prescription and process, which is time-consuming and costly. money. Although the results of in vivo and inRead more

Factors Influencing the Dissolution of Solid Dosage Forms

Method for Checking the Water Content in the Development of Solid Dosage Forms

Medicines are the foundation for human survival and social development, and are related to people's lives, health and safety. In the research and development of solid dosage forms, some drugs need to be treated with water, and some need to be added with a certain amount of liquid excipients. Improper operation will affect the qualityRead more

Method for Checking the Water Content in the Development of Solid Dosage Forms

Selection of Excipients for Oral Solid Dosage Process Research

It is well known that medicine is a special commodity that can meet people's needs for treatment and rescue. However, pharmaceutical preparations involve a lot of content in the process of research and development. In drug development, it may be affected by such things as low level of drug development, more repetitive drugs, and drugRead more

Selection of Excipients for Oral Solid Dosage Process Research

What are the methods for improving yeast two-hybrid technology?

Yeast two-hybrid technology, as the main method of studying protein interaction, occupies a pivotal position in large-scale protein interaction research, and has become an important experimental method in the field of molecular biology research. Therefore, many biological companies provide everything from constructing hybrid libraries to One-stop yeast two-hybrid service for library screening. However, the molecularRead more

What are the methods for improving yeast two-hybrid technology?

Application of Yeast Two-hybrid Technology in Screening Drugs and Finding Drug Targets

The yeast two-hybrid system is an important technical means for studying protein-protein interactions, and is now also being used in high-throughput screening of interacting proteins and other related molecules. Yeast transformation is simple and efficient. After the yeast two-hybrid library is constructed, it is relatively easy to directly screen out positive clones that interact betweenRead more

Application of Yeast Two-hybrid Technology in Screening Drugs and Finding Drug Targets

Yeast two-hybrid technology can be used to screen LKB1 interacting proteins

It is well known that proteins play a very key role in the process of cell life activities. The understanding of protein interactions can better understand the essence of life. The yeast two-hybrid system is an effective genetic method for analyzing protein interactions in vivo. In the yeast two-hybrid experiment service provided by some biomedicalRead more

Yeast two-hybrid technology can be used to screen LKB1 interacting proteins

Analysis on the Method of Yeast Two-hybrid Library Construction

Yeast two-hybrid technology is an important experimental method in the field of molecular biology research. It uses yeast genetics to analyze the interactions between proteins. It has now been widely used in proteomics, cell signal transduction, and functional genomics. . Yeast two-hybrid library construction generally includes two methods: nuclear system and membrane system. The nuclearRead more

Analysis on the Method of Yeast Two-hybrid Library Construction

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