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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Feb 02,2017
Artificial Skin Feels Temperature Changes
    Through a special organ on their snouts, pit vipers can sense the body heat of their prey. Scientists at Caltech and ETH Zurich have developed an artificial skin that uses a similar mechanism and could allow prosthetic limbs to detect changes in temperature, or make a smart bandage that can warn of infection.  The materialRead more
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Artificial Skin Feels Temperature Changes
Feb 02,2017
Stem Cell Exosomes Convey Hope for Cell-Free Glaucoma Treatment
    Ideally, a stem cell therapy wouldn't require the actual administration of stem cells. Even stem cells that secrete helpful compounds can lead to complications. For example, stem cells can lead to immune rejection and unwanted cell growth.     In hopes of avoiding such complications in stem cell therapies meant to protect against glaucoma and other eyeRead more
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Feb 01,2017
New Insight Describes Connection between Salmonella Infection and Appetite Loss
The old "feed a cold, starve a fever” saying has been reexamined countless times, but always from the host's point of view. Isn't it time to ask what the pathogen thinks? That's the question that occurred to a team of Salk Institute scientists. These scientists studied how an intestinal pathogen, Salmonella Typhimurium, blocks the appetite-lossRead more
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New Insight Describes Connection between Salmonella Infection and Appetite Loss
Feb 01,2017
Transcription Factor Is Lynchpin to Fighting Viral Infections
    In a world of emerging and devastating viral infections such as Zika, Ebola, and influenza, the importance of understanding how viruses target our immune system, and the need to develop new therapies, has never been greater. Now, a team of scientists at Trinity College Dublin has discovered that a biological molecule important in cell growthRead more
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Transcription Factor Is Lynchpin to Fighting Viral Infections
Jan 31,2017
CD99 Targeted as Novel Approach for Treatment of Acute Myeloid Leukemia
    Acute myeloid leukemia (AML) is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal white blood cells that build up in the bone marrow and interfere with the production of normal blood cells. AML is the most common acute leukemia affecting adults, and its incidence increases with age.Read more
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Jan 31,2017
How Tumor Cells Hide from Chemo After Metastasizing
    Researchers at the Mount Sinai School of Medicine say they have discovered the conditions by which specific signals in primary tumors of head and neck and breast cancers preprogram cancer cells to become dormant and evade chemotherapy after spreading. Their findings (“Phenotypic Heterogeneity of Disseminated Tumour Cells Is Preset by Primary Tumour Hypoxic Microenvironments”), publishedRead more
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Jan 30,2017
Natural Celery Molecule Inhibits Triple-Negative Breast Cancer Growth
    In culinary preparation, mirepoix is often used as the basis for a multitude of dishes. Now, a molecule that resides in one of the members of this foundational trinity—traditionally consisting of celery, carrots, and onions—could potentially improve the treatment of the devastating trinity, triple-negative breast cancer.     Investigators at the University of Missouri (MU) found thatRead more
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Jan 30,2017
Parkinson's Protein Has Widespread and Conserved Toxicity Influence
    Through two publications and a large collaboration, led by researchers at Whitehead Institute and Massachusetts Institute of Technology (MIT), investigators have just described their use of a suite of novel biological and computational methods to shed light on how the misfolding of α-synuclein protein in neurons relates to the growing number of genes implicated inRead more
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Parkinson's Protein Has Widespread and Conserved Toxicity Influence
Jan 27,2017
Study Finds Fly Growth Mimics Cancer Cells
Scientists who study a molecule known to play a role in certain types of cancers and neurodegenerative disorders have a powerful new tool to study this compound due to research conducted at Indiana University (IU). Their study ("Drosophila Larvae Synthesize the Putative Oncometabolite L-2-Hydroxyglutarate during Normal Developmental Growth”), published in the Proceedings of the National Academy of Sciences.
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Study Finds Fly Growth Mimics Cancer Cells
Jan 27,2017
Immunotherapy Coalesces on Platelets as Drug Delivery Mechanism
    Maintaining hemostasis (stop bleeding) is the main function of thrombocytes—commonly referred to as platelets. Yet, what if these cells could be engineered to carry anticancer drugs to wipe out those microtumors? Well, scientists at the University of North Carolina (UNC) and North Carolina State University (NC State) have developed a way to do just that,Read more
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Immunotherapy Coalesces on Platelets as Drug Delivery Mechanism