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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Feb 14,2017
Alternative Theory on How Aspirin May Thwart Cancer
Studies abound that point to a role for plain old aspirin in keeping deadly cancers at bay. While aspirin is not yet part of mainstream treatment for any cancer, it is recommended by the U.S. Preventive Services Task Force for certain adults to help prevent colorectal cancer. Scientists have puzzled for years over how exactlyRead more
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Feb 14,2017
Circular DNA Helps Cancer Roll with the Therapeutic Punches
    Extrachromosomal DNA is any DNA that is found outside of the nucleus of a cell. It is also referred to as extranuclear DNA or cytoplasmic DNA. Most DNA in an individual genome is found in chromosomes but DNA found outside of the nucleus also serves important biological functions.         In the evolution of cancer,Read more
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Circular DNA Helps Cancer Roll with the Therapeutic Punches
Feb 14,2017
IND Enabling Studies FDA
Medicilon provide the IND filing for the preclinical services. Medicilon could submit the application for both US FDA and CFDA for your new drug. Medicilon is the first CRO to offer preclinical animal testing service for the global pharmaceutical companies in China. Medicilon is the CRO that fulfill both the Chinese and US GLP standards.Read more
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IND Enabling Studies FDA
Feb 13,2017
Proteomics Service Company
Proteomics is the systematic identification and characterization of proteins, their structures and functions.  Medicilon has extensive experience in the analyses of protein using advanced technology including mass spectrometry and bioinformatics. The facility provides support, equipment and expertise for analyzing complex protein mixtures.  We work with each client to determine the best approach and services neededRead more
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Proteomics Service Company
Feb 13,2017
Nano-CRISPR Packages Attain 90% Delivery Rate with Engineered Cas9
Neither the cell membrane nor the cytoplasm nor the nuclear membrane stays these couriers from the swift completion of their appointed rounds. "These couriers” are nanoparticles that carry Cas9-ribonucleoprotein (RNP) complexes into the cytoplasm and nucleus of target cells, and do so with uncommon efficiency. Newly developed by scientists in Vincent Rotello's laboratory at theRead more
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Nano-CRISPR Packages Attain 90% Delivery Rate with Engineered Cas9
Feb 13,2017
Protein Trafficking Roadblocks Could Be Cause of Neurodegeneration
A new collaborative study from investigators at the Chinese Academy of Sciences and the University of Manchester has just uncovered that shutting down the flow of proteins within a uniquely named cell organelle—the Golgi apparatus—could be a major underlying cause of neurodegeneration. The team of researchers examined the role of the Golgi apparatus in neuronsRead more
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Protein Trafficking Roadblocks Could Be Cause of Neurodegeneration
Feb 10,2017
New DNA Repair Finding Could Lead to Novel Antibacterial Drugs
    Antibacterial drugs are derived from bacteria or molds or are synthesized de novo. Technically, "antibiotic” refers only to antimicrobials derived from bacteria or molds but is often used synonymously with "antibacterial drug.”         Researchers from the University of North Carolina (UNC) School of Medicine say they have confirmed and clarified the key molecular detailsRead more
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New DNA Repair Finding Could Lead to Novel Antibacterial Drugs
Feb 10,2017
Search for Synthetic-Essential Genes Uncovers Prostate Cancer Treatment Target
    A new method has been found for identifying therapeutic targets in cancers lacking specific key tumor suppressor genes. The process, which located a genetic site for the most common form of prostate cancer, has potential for developing precision therapy for other cancers, such as breast, brain, and colorectal, say researchers at The University of TexasRead more
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Search for Synthetic-Essential Genes Uncovers Prostate Cancer Treatment Target
Feb 10,2017
Biomarker Testing and Analysis
At Medicilon, we have over 10 years' experience in biomarker analysis services and we operate two of our own GLP laboratories.  We provide biomarker testing and analysis services to support preclinical research of new therapeutics. We perform biomarker assay development and validation using single and multiplex LC/MS/MS, MSD, ELISA, and enzyme activity techniques.
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Biomarker Testing and Analysis
Feb 09,2017
Marijuana Compound Shows Some Potential for Treating Opioid Addiction
    In 2014, more people died from drug overdoses than at any other time in U.S. history, with 60% of fatalities involving opioid drugs. Moreover, estimates point to between 26 and 36 million people abusing opioids worldwide, with roughly 2.1 million people in the U.S. suffering from substance use disorders related to prescription opioid pain relievers.Read more
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