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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Mar 10,2017
Caffeine Boosts Enzyme That Could Protect Against Dementia
    Caffeine is a bitter substance found in coffee, tea, soft drinks, chocolate, kola nuts, and certain medicines. It has many effects on the body's metabolism, including stimulating the central nervous system. This can make you more alert and give you a boost of energy.         Scientists at Indiana University have identified 24 compounds, includingRead more
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Caffeine Boosts Enzyme That Could Protect Against Dementia
Mar 10,2017
DNA Motors in Living Cells Start with MicroRNA Keys
Synthetic DNA motors have great potential to mimic natural protein motors in cells but the operation of synthetic DNA motors in living cells remains challenging and has not been demonstrated. Yet DNA motors built by scientists at the University of Alberta have been running smoothly inside cancer cells. Also, each of these molecular engines didn'tRead more
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DNA Motors in Living Cells Start with MicroRNA Keys
Mar 09,2017
Cargo-Carrying Red Blood Cells Alleviate Autoimmune Diseases in Mice
An autoimmune disease is one in which the immune system mistakenly attacks the body's own cells, tissues, and organs. There are more than 80 autoimmune diseases, and the more common ones include type 1 diabetes, multiple sclerosis (MS), systemic lupus erythematosus, rheumatoid arthritis, and inflammatory bowel disease. Using red blood cells modified to carry disease-specificRead more
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Cargo-Carrying Red Blood Cells Alleviate Autoimmune Diseases in Mice
Mar 09,2017
Painkillers Without Dangerous Side Effects
    Opioids are a class of strong pain killers. They are mainly used to treat pain associated with tissue damage and inflammation, such as that caused by surgery, nerve damage, arthritis or cancer.  Opioids, like sledgehammers, are powerful but blunt tools. When they are used to flatten pain, opioids may give other things a pounding, too.Read more
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Painkillers Without Dangerous Side Effects
Mar 08,2017
Scientists Have Created A Way to Delete DNA in Living Cells
    Until recently, genomics was a "read-only” science, but scientists have developed a tool for quick and easy deletion of DNA in living cells. This software, published in PLOS Computational Biology, will boost efforts to understand the vast regions of non-coding DNA, or "Dark Matter”, in our DNA and may lead to discovery of new disease-causingRead more
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Scientists Have Created A Way to Delete DNA in Living Cells
Mar 08,2017
Lab-Grown Embryo Breakthrough May Relieve Research Bottleneck
    The artificial mouse embryo is a major step toward creating synthetic embryos that closely resemble natural ones. It could shed light on early development and help improve fertility treatment procedures.     Cambridge biologist Magdalena Zernicka-Goetz, whose work focuses on the development of cell lineages, has long sought the development of an artificial embryo. But without usingRead more
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Lab-Grown Embryo Breakthrough May Relieve Research Bottleneck
Mar 07,2017
Brain Protein Discovery Offers Hope for Alzheimer's Patients
    An estimated 1 in 3 seniors dies with one form of dementia. Affecting more than 5 million people in the United States, Alzheimer's disease is the most common form of dementia; it accounts for well over half of all cases.     Alzheimer's is characterized by an accumulation of amyloid plaques between nerve cells. Amyloid is aRead more
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Brain Protein Discovery Offers Hope for Alzheimer's Patients
Mar 07,2017
Comprehensive Atlas of Long Noncoding RNAs Yields Surprising New Role
    The Central Dogma of molecular biology states that DNA encodes RNA, RNA encodes protein. While this process is certainly true for the vast majority gene regulatory functions, in recent years, scientists have discovered that this is by no means an exclusive process. In fact, studies examining the association between genes and diseases have shown thatRead more
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Comprehensive Atlas of Long Noncoding RNAs Yields Surprising New Role
Mar 06,2017
Genome Mining of Natural Products Could Lead to Novel Therapeutics
    In an age of booming biotechnology, it might be easy to forget how much we still rely on the bounty of the natural world. Some microbes make us sick; some keep us healthy, while others continue to give us some of our best cures in the form of naturally occurring products such as penicillin andRead more
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Genome Mining of Natural Products Could Lead to Novel Therapeutics
Mar 06,2017
Small Subset of Proteins Cannot Take the Heat
    Rather than poach proteins singly, scientists at ETH Zurich turned up the heat on entire proteomes. Some proteins proved to be especially sensitive to heat, collapsing or denaturing sooner than most of their peers. Even though the most sensitive proteins represent a minority, they are, apparently, crucial to cell survival. Without these proteins, cells perishRead more
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Small Subset of Proteins Cannot Take the Heat