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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Mar 29,2017
Debilities of Aging Reversed by Protein That Targets Senescent Cells
    Relieved of the burden of senescent cells, we may enjoy extended healthspans—or even lifespans. This notion was put to the test by a team of scientists based at Erasmus University Medical Center. They selectively eliminated senescent cells in aging mice, which responded by showing a reversal of age-related loss of fur, poor kidney function.
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Debilities of Aging Reversed by Protein That Targets Senescent Cells
Mar 29,2017
Neurodegenerative Disease Associated with New Gene Variant
    Neurodegenerative diseases are a heterogeneous group of disorders that are characterized by the progressive degeneration of the structure and function of the central nervous system or peripheral nervous system. Common neurodegenerative diseases include Alzheimer's disease and Parkinson's disease.         Investigators at Rush University Medical Center and the Brigham and Women's Hospital in Boston reportedRead more
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Neurodegenerative Disease Associated with New Gene Variant
Mar 28,2017
Scientists Convert Spinach Leaves Into Human Heart Tissue
    It looks like spinach is more than just good for you to eat – it could be an asset to human tissue and organ regeneration.  Researchers from the Worcester Polytechnic Institute, the University of Wisconsin–Madison and Arkansas State University–Jonesboro placed human heart cells onto spinach leaves stripped of plant cells – effectively creating working humanRead more
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Mar 28,2017
Epigenetics Plays a Major role in Breast Cancer Resistance
    Breast cancer's ability to develop resistance to treatment has frustrated researchers and physicians and has thwarted even the latest and greatest targeted therapies. For example, after researchers identified a disease pathway integral to many breast cancers called PI3K, they began testing experimental drugs that block this pathway — only to see the tumors then activateRead more
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Epigenetics Plays a Major role in Breast Cancer Resistance
Mar 28,2017
Standardization of Clinical Trials to Upgrade New Drug CRO to Seek Strategic Transformation
Since the CFDA formally issued the "Announcement on Carrying out Self-Inspection and Verification of Drug Clinical Trial Data (2015 No. 117)” in July 2015, the upgrading of the quality of drug clinical trial supervision has had a significant impact on CRO companies in the past 2016. Big impact: the sponsor actively withdraws applications, the numberRead more
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Mar 28,2017
Drug Bioavailability Studies from Medicilon
Bioavailability is defined as the rate and the absorption of drug that reaches the biological system in an active form, capable of exerting the desired pharmacological effect, including its onset, intensity and duration of its action. The Need for Bioavailability Studies Bioavailability studies provide and estimate of the fraction of the orally administered dose thatRead more
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Drug Bioavailability Studies from Medicilon
Mar 27,2017
Bioequivalence Studies for Generic Drugs
Two different drugs or formulations of the same drug are called bioequivalent if they are absorbed into the blood and become available at the drug action site at about the same rate and concentration. Bioequivalence studies is usually studied by administering dosages to subjects and measuring concentration of the drug in the blood just beforeRead more
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Bioequivalence Studies for Generic Drugs
Mar 27,2017
New Genetic Test Could Provide Answer If You Are at Risk for Alzheimer
    The ability to determine the risk of contracting any disease is powerful information to have for both patients and healthcare providers. For Alzheimer's disease (AD), in which risk factors have been notoriously elusive, any potential insight into who may be at risk to develop the neurodegenerative disorder could help alleviate a significant amount of burdenRead more
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New Genetic Test Could Provide Answer If You Are at Risk for Alzheimer
Mar 27,2017
Strangle Proteins in the Ribosomal Cradle, Selectively
If a fully formed protein is known to mediate disease, it might seem like a good idea to keep the protein from developing in the first place, to nip it in the bud, so to speak. And, in fact, agents have been found that can prevent protein translation by stalling the ribosome, the general-purpose molecularRead more
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Strangle Proteins in the Ribosomal Cradle, Selectively
Mar 24,2017
Parsley and Other Plants Lend Form to Human Stem Cell Scaffolds
    Borrowing from nature is an age-old theme in science. Form and function go hand-in-hand in the natural world and the structures created by plants and animals are only rarely improved on by humans.         Researchers at the University of Wisconsin–Madison are using the decellularized husks of plants such as parsley, vanilla, and orchids toRead more
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