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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Apr 21,2017
Bacteriophages and Natural Drugs to Combat Superbugs
Viruses that specifically kill bacteria, called bacteriophages, might one day help solve the growing problem of bacterial infections that are resistant to antibiotic treatment. Originally proposed as a therapeutic tool by French-Canadian microbiologist Félix d'Herelle in 1926, looking at these viral invaders again may help solve the growing problem of bacterial infections that are resistant.
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Bacteriophages and Natural Drugs to Combat Superbugs
Apr 21,2017
Master Detox Molecule Boosts Immune Defenses
The immune system is a host defense system comprising many biological structures and processes within an organism that protects against disease. To function properly, an immune system must detect a wide variety of agents, known as pathogens, from viruses to parasitic worms, and distinguish them from the organism's own healthy tissue.     Glutathione (GSH),Read more
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Master Detox Molecule Boosts Immune Defenses
Apr 21,2017
Biomedical Outsourcing Can Cut New Drug Research Costs Greatly
New drug research is complex system engineering, including compound research, preclinical research, clinical research, drug registration application and approval, and post-marketing research, with the features of long cycle and high cost and risk. According to a survey of Tufts Center, the average cost of new drug research has risen from $ 802 million in 2003Read more
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Biomedical Outsourcing Can Cut New Drug Research Costs Greatly
Apr 20,2017
Bioanalytical Laboratory Services of Medicilon
The Bioanalysis Department of Medicilon provides a comprehensive bioanalytical services compliance with FDA/OECD/CFDA GLP requirement. With a capacity to analyze more than 250,000 samples per year, Medicilon is uniquely positioned to handle the demands of "fast PK studies” in a wide variety of animal matrices in order to provide streamlined fast feedback using appropriate methods.Read more
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Bioanalytical Laboratory Services of Medicilon
Apr 20,2017
Immunotherapy for Glioblastoma Well Tolerated,Survival Gains Observed
    A phase one study of 11 patients with glioblastoma who received injections of an investigational vaccine therapy and an approved chemotherapy showed the combination to be well tolerated while also resulting in unexpectedly significant survival increases, researchers at the Duke Cancer Institute report.     Patients treated with the study drug (dose-intensified temozolomide and vaccines) were continuouslyRead more
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Immunotherapy for Glioblastoma Well Tolerated,Survival Gains Observed
Apr 20,2017
Alerting Stem Cells to Speed Up and Heal
    Accelerated healing isn’t just for superheroes.  Scientists report in a paper ("HGFA Is an Injury-Regulated Systemic Factor that Induces the Transition of Stem Cells into GAlert ") in Cell Reports about a new approach to speed recovery from a wide variety of injuries.     "Our research shows that by priming the body before an injury, you can speedRead more
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Apr 20,2017
Obesity and Diabetes Might Be Treated by Targeting Two BAT Cell Receptors
    Researchers say they have discovered a way to increase the amount of metabolism-boosting brown adipose tissue (BAT) ("good” fat) by employing two receptors on BAT cells as potential therapeutic targets. Both receptors, TRPM8 and TRPP3, are associated with the creation of BAT in humans and may be activated by certain foods, and possibly the envisionedRead more
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Obesity and Diabetes Might Be Treated by Targeting Two BAT Cell Receptors
Apr 19,2017
Melanoma Thwarted by Resident Memory T Cells
Unique immune cells, known as resident memory T cells, do an excellent job of preventing melanoma, scientists at Norris Cotton Cancer Center of Dartmouth University report in a newly published study.  Their finding stems from an investigation of why patients with melanoma who develop the autoimmune disease called vitiligo have such good prognosis.
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Melanoma Thwarted by Resident Memory T Cells
Apr 19,2017
Cancer Stem Cells: Understanding Tumor Hierarchy and Heterogeneity
    Early evidence of intratumor heterogeneity came from experiments in which tumor cells from murine cancers were extracted and introduced into syngeneic hosts. It was determined that not all transplanted cells could reconstitute tumors.Similarly, varying numbers of metastatic colonies resulting from injection of syngeneic mice with murine melanoma tumor-derived cells suggested that the parent tumor harboredRead more
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Cancer Stem Cells: Understanding Tumor Hierarchy and Heterogeneity
Apr 19,2017
New Plant Gene Network Could Significantly Improve Drug Discovery
    The contribution that plants make to the drug discovery process is indispensable. Yet, identifying the networks of genes that plants use to make these biologically active compounds has vexed scientists for years, hindering efforts to tap this vast pharmacopeia to produce new and improved therapeutics. Now, a team of geneticists led by investigators at VanderbiltRead more
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New Plant Gene Network Could Significantly Improve Drug Discovery