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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Apr 27,2017
Development Trend of Medicinal Chemistry
The progress of medicinal chemistry and a large number of new drugs listed in the late 20th century, mainly summarized as two reasons: 1) Life sciences, such as structural biology, molecular biology, molecular genetics, genetics and biotechnology, to provide theoretical basis and technical support for the discovery of new drugs; 2) the rapid development ofRead more
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Development Trend of Medicinal Chemistry
Apr 26,2017
Protein Production Systems and Purification
The prokaryotic protein expression system is both the most commonly used expression system and the most economical one. The prokaryotic expression system is represented by Escherichia coli expression system, which has the advantages of clear genetic background, low cost, high expression and relatively simple separation and purification of expressed products.  The disadvantages are mainly theRead more
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Protein Production Systems and Purification
Apr 26,2017
Blood Pressure Drug May Help Treat Skin Cancer
  A new study finds that carvedilol, a drug typically used to treat high blood pressure, can protect against the sun-induced cell damage that leads to skin cancer. Researchers serendipitously discovered the beta blocker's cancer-fighting properties after making an error in the lab.
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Apr 26,2017
New Mass Spec Method Quickly Identifies Drug-Resistant Microbes
    Rapid identification of clinical samples for dangerous and drug-resistant types of bacterial infections is essential for physicians to accurately diagnose patients and administer the appropriate drug therapy. Now, new research from a team of scientists describes a method for quickly assessing microbial pathogenesis using equipment already owned by most hospitals. The researchers presented their dataRead more
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New Mass Spec Method Quickly Identifies Drug-Resistant Microbes
Apr 25,2017
Naked Mole Rats Use Glucose-Fructose Switch to Survive Suffocating Conditions
    Naked mole rats are famous for their lovable ugliness, their extremely long lives, their ability to evade cancer, and now, too, their capacity to survive without oxygen for 18 minutes.  Renowned for its longevity, resistance to cancer, and ability to adopt the ambient temperature as its own body temperature, this unprepossessing rodent, this cold-blooded mammal,Read more
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Naked Mole Rats Use Glucose-Fructose Switch to Survive Suffocating Conditions
Apr 25,2017
Molecular Biology Advances the Entire Medical Science to the Molecular Level
Classical biology can only describe and summarize certain laws of life activity from changes in biological phenotypes. The so-called genes are only abstract concepts, and the molecular basis of phenotypes is not identified. The same is true of previous medical research. Only molecular biology research has led to the rise of medical science to theRead more
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Molecular Biology Advances the Entire Medical Science to the Molecular Level
Apr 25,2017
Cause of Stroke Immunodeficiency Uncovered
    As if the devastating effects on the brain after having a stroke weren't enough, new research from investigators at the Roslin Institute, located on the University of Edinburgh’s Easter Bush Campus, points to immune cells being damaged as a result of the acute neurologic event. Findings from the new study—published recently in Nature Communications inRead more
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Apr 24,2017
Key Microscopy Advance May Open Door to New Therapies for Disease
Scientists at Columbia University say they have made a significant step toward breaking the so-called "color barrier” of light microscopy for biological systems, allowing for much more comprehensive, system-wide labeling and imaging of a greater number of biomolecules in living cells and tissues than is currently attainable. The advancement has the potential for many futureRead more
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Key Microscopy Advance May Open Door to New Therapies for Disease
Apr 24,2017
Amino Acids in Diet Could Be Key to Starving Cancer
Cancer cells have an unnatural appetite for certain amino acids—nonessential amino acids that healthy cells produce themselves, usually in amounts sufficient for ordinary metabolism. If cancer cells are denied these amino acids, they are weakened.
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Amino Acids in Diet Could Be Key to Starving Cancer
Apr 21,2017
A Molecular ON AND OFF Switch for CRISPR
    For many bacteria, one line of defense against viral infection is a sophisticated RNA-guided “immune system” called CRISPR-Cas. At the center of this system is a surveillance complex that recognizes viral DNA and triggers its destruction. However, viruses can strike back and disable this surveillance complex using “anti-CRISPR” proteins, though no one has figured outRead more
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