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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
May 09,2017
Nano Catapult to Target Disease
An international team of researchers from the University of Rome Tor Vergata and the University of Montreal has reported, in a paper published in Nature Communications, the design and synthesis of a nanoscale molecular slingshot made of DNA that is 20,000 times smaller than a human hair. This molecular slingshot could "shoot” and deliver drugsRead more
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Nano Catapult to Target Disease
May 08,2017
Novel Tool Confers Targeted, Stable Editing of Epigenome in Human Stem Cells
    Salk Institute scientists have developed a novel technology to correct disease-causing aberrations in the chemical tags on DNA that affect how genes are expressed. These types of chemical modifications, collectively referred to as epigenetics or the epigenome, are increasingly being considered as important as the genomic sequence itself in development and disease.     The new SalkRead more
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Novel Tool Confers Targeted, Stable Editing of Epigenome in Human Stem Cells
May 08,2017
Synthetic Biology Provides New Approach to Antibiotic Production
    The synthetic biologists from Imperial College London have re-engineered yeast cells to manufacture the nonribosomal peptide antibiotic penicillin. In laboratory experiments, they were able to demonstrate that this yeast had antibacterial properties against streptococcus bacteria.           The authors of the study ("Biosynthesis of the Antibiotic Nonribosomal Peptide Penicillin in Baker's Yeast”), which is published in NatureRead more
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Synthetic Biology Provides New Approach to Antibiotic Production
May 08,2017
Immunotherapy Advanced by Immune Cell Studies of Lung and Kidney Cancers
    Two independent studies have begun mapping connections among the thousands of immune cells surrounding human tumors. One research group, looking at kidney cancer, found that tumors with different clinical outcomes have unique immune cell profiles that can also estimate a cancer patient's prognosis. The other team, looking at lung cancer, showed that even early tumorsRead more
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Immunotherapy Advanced by Immune Cell Studies of Lung and Kidney Cancers
May 05,2017
Exercise Pill Boosts Endurance, Promotes Burning of Fat
    Every week, there seems to be another story about the health benefits of running. That's great — but what if you can't run? For the elderly, obese or otherwise mobility-limited, the rewards of aerobic exercise have long been out of reach.  This question has been raised by a new study that suggests the path betweenRead more
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Exercise Pill Boosts Endurance, Promotes Burning of Fat
May 05,2017
Beta Cell Growth Finding May Lead to Improved Therapies for Diabetics
    Using single-cell RNA sequencing, researchers at University of California, San Diego School of Medicine have, for the first time, mapped out pathways that regulate beta cell growth that could be exploited to trick them to regenerate.     Pancreatic β cells help maintain normal blood glucose levels by producing the hormone insulin, the master regulator of energyRead more
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May 04,2017
Eliminating HIV in Live Animals Using CRISPR
    The human immunodeficiency virus (HIV) is a lentivirus that causes HIV infection and over time acquired immunodeficiency syndrome (AIDS). AIDS is a condition in humans in which progressive failure of the immune system Allows life-threatening opportunistic infections and cancers to thrive.       Due to their innate nature to hide away and remain latent for extendedRead more
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Eliminating HIV in Live Animals Using CRISPR
May 04,2017
One Gene to Start Them All
    No magical object is needed for zygotic genome activation (ZGA), the process that initiates gene transcription in newly fertilized oocytes, and thereby unleashes the genome's latent powers. Instead, some of the earliest stages of embryonic development come down to an ordinary-seeming gene, one that has an unprepossessing name: DUX.
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One Gene to Start Them All
May 03,2017
Alcohol Linked to Increased Risk of Breast Cancer in African-Americans
    Alcohol consumption was associated with an increased risk of breast cancer in a large study of African-American women, indicating that they, like white women, may benefit from limiting alcohol. These study results have been published in Cancer Epidemiology, Biomarkers & Prevention, the journal of the American Association for Cancer Research. The lead author is MelissaRead more
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Alcohol Linked to Increased Risk of Breast Cancer in African-Americans
May 03,2017
Stem Cells in Culture Have Tendency to Develop Cancer-Linked Mutations
Stem cells that are grown in the lab are known to acquire mutations, but whether these mutations are particularly numerous or risky remains unclear. Mutations acquired in stem cell culture, it is feared, would complicate efforts to deploy stem cells in regenerative medicine. At the least, lab-grown stem cells may need to be screened forRead more
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Stem Cells in Culture Have Tendency to Develop Cancer-Linked Mutations