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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Jul 25,2017
Shooting the Achilles Heel of Nervous System Cancers
Virtually all cancer treatments used today also damage normal cells, causing the toxic side effects associated with cancer treatment.  A team led by scientists at Dartmouth's Norris Cotton Cancer Center says it has devised a strategy to target cancer cells while sparing normal cells. This strategy capitalizes on the fact that processes that allow aRead more
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Shooting the Achilles Heel of Nervous System Cancers
Jul 25,2017
Team Uses ARGO Methodology to Follow Dengue Outbreaks
Dengue, a mosquito-borne virus that infects about 390 million people each year, is often difficult to monitor with traditional hospital-based reporting due to inefficient communication. Researchers from Harvard have developed an analytical tool that combines Google search data with government-provided clinical data to track dengue fever in less-developed countries. The team published its study ("AdvancesRead more
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Jul 25,2017
hERG Assay – Drug Preclinical Cardiac Safety Assessment
Cardiac safety assessment is an important factor that all kinds of new drugs must be investigated before entering the clinical trial. It is also one of the most important and difficult links in the early clinical research of innovative drugs. In recent years, some drugs that have been put into clinical use have received widespreadRead more
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hERG Assay – Drug Preclinical Cardiac Safety Assessment
Jul 25,2017
In Vitro Metabolism Studies Services
In vitro metabolism studies can exclude the interference of the body factors for the overall experiment to provide a reliable theoretical basis for the low metabolic rate in vivo, toxic and lack of sensitive detection means of drugs, in vitro metabolism research is a good means of research. At present, in vitro models of drugRead more
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In Vitro Metabolism Studies Services
Jul 25,2017
Compounds Solubility Test
Intrinsic solubility refers to the drug does without any impurities in the solvent and occur dissociation or association, nor the interaction occurred when the concentration of saturated solution is one of the important physical parameters of the drug, especially for new compounds. From the point of view of formulation, the solubility of a new drugRead more
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Compounds Solubility Test
Jul 24,2017
Lunatic Fringe Gene Plays Key Role in Renewable Brain
A long-standing misconception in biology, until recently, had been that the adult brain did not generate new neuronal cells. However, the point of fact is that the brain can produce slightly under a thousand new neurons per day on average. Yet, how this process is regulated molecularly is still a bit of a mystery toRead more
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Lunatic Fringe Gene Plays Key Role in Renewable Brain
Jul 24,2017
Protein Identified That May Decrease Radiation Side Effects
More than half of cancer patients undergo radiotherapy, in which high doses of radiation are aimed at diseased tissue to kill cancer cells. But due to a phenomenon known as radiation-induced bystander effect (RIBE), in which irradiated cells leak chemical signals that can travel some distance to damage unexposed healthy cells, many suffer side-effects suchRead more
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Protein Identified That May Decrease Radiation Side Effects
Jul 21,2017
Drug Delivery Could Become Smooth as Silk
Wrapping oneself up in a protective cocoon and hibernating the day away is probably an attractive idea for many people. Take your favorite media device with you, and it might even be a great way to catch up on your binge TV watching. While scientists are no strangers to the appeal of cocooning themselves fromRead more
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Drug Delivery Could Become Smooth as Silk
Jul 21,2017
Targeting CD44s Molecule May Open New Door to Improved Cancer Therapies
Scientists at the Baylor College of Medicine have discovered that the molecule CD44s seems to give cancer cells a survival advantage. In the lab, eliminating this advantage by reducing the amount of CD44s resulted in cancer cells being more sensitive to the deadly effects of the drug erlotinib. The team's study ("Internalized CD44s Splice IsoformRead more
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Jul 21,2017
Non Human Primate Research
For more than ten years experience, Medicilon provides service of prelinical studies in non-human primates cro.  Studies in non-human primates are the final stage of preclinical development and provide data close to results seen in human studies. Medicilon Offers the Following Studies Safety Pharmacology Studies Toxicological Research Pharmacokinetics and Toxicokinetics Research Studies of Primate BehaviorRead more
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Non Human Primate Research