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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Aug 30,2017
When Two Immunotherapy Rights Make a Wrong
Recent advances in immunotherapy have given many cancer patients stricken with tumors intractable to current therapies hope for meaningful remission times. While researchers continue to try and understand the intricacies of the immune system's response to carcinogenesis, many clinicians are looking for combinations of immunotherapy compounds to provide an even greater response to cancer suppression.Read more
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When Two Immunotherapy Rights Make a Wrong
Aug 29,2017
Magic Mushrooms Break on Through to Biosynthetic Reality
Psilocybin, the psychedelic substance in so-called magic mushrooms, has been used in religious rituals, in recreational and mind-altering pursuits, and in medical studies. Although psilocybin revealed its structural details 60 years ago, and although this psychoactive substance has been tested for its ability to lessen anxiety, relieve depression, and loosen the grip of addiction, psilocybinRead more
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Magic Mushrooms Break on Through to Biosynthetic Reality
Aug 29,2017
Immunotherapy Triggers Release of Mitochondrial DNA and Trips Alarm
A place for everything and everything in its place is a mantra that eukaryotic cells ascribe to with some frequency. For instance, DNA is compartmentalized to organelles like the nucleus and mitochondria. The cytosolic space is not typically an area where DNA is present unless the cell is under attack by some form of pathogen,Read more
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Immunotherapy Triggers Release of Mitochondrial DNA and Trips Alarm
Aug 29,2017
Acute Toxicity Test on Animals
Acute toxicity assessment is one of the basic types of in vivo and drug registration often requires acute toxicity evaluation. The data of the acute toxicity test have a special effect in safety evaluation, and MTD or MFD can be determined in the initial toxicity description. The data obtained in these trials can provide aRead more
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Acute Toxicity Test on Animals
Aug 28,2017
Manipulating A Single Gene Defines a New Pathway to Anxiety
Removing a single gene from the brains of mice and zebrafish causes these animals to become more anxious than normal. Researchers from University of Utah Health show that eliminating the gene encoding Lef1 disrupts the development of certain nerve cells in the hypothalamus that affect stress and anxiety.  Their study ("Lef1-Dependent Hypothalamic Neurogenesis Inhibits Anxiety”),Read more
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Manipulating A Single Gene Defines a New Pathway to Anxiety
Aug 28,2017
Advanced Nanodot System Improves Tumor Visualization
Researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) have developed a proof-of-concept nanosystem that dramatically improves the visualization of tumors. Their study ("In Vivo Cation Exchange in Quantum Dots for Tumor-Specific Imaging”), published in Nature Communications, the platform achieves a five-fold increase over existing tumor-specific optical imaging methods. The novel approach generates bright tumor signalsRead more
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Advanced Nanodot System Improves Tumor Visualization
Aug 25,2017
Cancer Onset May Be Caused by Immune System Fighting Viruses
The development of an advanced immune system to fight off microbial pathogens is a considerable part of the evolutionary success of multicellular organisms. Yet, like most success stories there is always a flip side. New evidence from investigators at the University of Colorado (CU) Cancer Center shows how the action of various immunity-based enzymes canRead more
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Aug 25,2017
More Than 99 Percent of the Microbes Inside Human are Unknown to Science
A new survey of DNA fragments circulating in human blood suggests our bodies contain vastly more diverse microbes than anyone previously understood. What's more, the overwhelming majority of those microbes have never been seen before, let alone classified and named. The new survey, which effectively enabled sampling of the whole body, was undertaken by scientistsRead more
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More Than 99 Percent of the Microbes Inside Human are Unknown to Science
Aug 25,2017
Animal Models for Anxiety and Depression
Stress, anxiety and depression are closely related to the phenomenon, most of the anxiety and depression patients have experienced severe psychological stress events. Thus, stress events are seen as a cause of anxiety and depression, or at least on genetic basis, which can lead to the generation of emotional disorders. Anxiety and Depression Animal modelsRead more
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Animal Models for Anxiety and Depression
Aug 25,2017
Analytical Chemistry and Its Application Scope
Do you know the Analytical Chemistry and Its Application Scope? The main task of Analytical Chemistry is to identify the chemical composition (elements, ions, functional groups, or compounds) of the substance, to determine the content of the relevant components of the substance and the structure of the substance (chemical structure, crystal structure, spatial distribution), theRead more
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Analytical Chemistry and Its Application Scope