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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Sep 28,2017
What are the three major in vitro pharmacokinetic research methods?
In vitro incubation with liver microsomes, recombinant CYP450 enzyme lines, and in vitro incubation with hepatocytes are some of the more common in vitro drug metabolism research methods.
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What are the three major in vitro pharmacokinetic research methods?
Sep 28,2017
The Pharmaceutical Preparation Process Enlarged Service
Medicilon has the professional formulation technical platform and the most experienced team, which could offer fully integrated pharmaceutical services to meet different requirements of our clients. We focus on the development of solid dosage forms, semisolid dosage forms, liquid dosage forms and sterile dosage forms. Our formulation group is also highly experienced in developing sustained
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The Pharmaceutical Preparation Process Enlarged Service
Sep 27,2017
Flesh-Eating Bacteria Carry Genes for Getting Under Your Skin, and Thriving
Group A Streptococcus bacteria cause a variety of illnesses that range from mild nuisances like strep throat to life-threatening conditions including pneumonia, toxic shock syndrome and the flesh-eating disease formally known as necrotizing fasciitis. The life-threatening infections occur when the bacteria spread underneath the surface of the skin or throat and invade the underlying softRead more
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Sep 27,2017
Protein Linking Key Organelles May Shed Light on Neurodegenerative Disease Development
Scientists report that they have developed a technique to identify proteins that allow the mitochondria and the endoplasmic reticulum to attach to each other. Faulty connections between the ER and mitochondria have been implicated in several neurodegenerative diseases, including Alzheimer's, Parkinson's, and Huntington's diseases. The research ("Ascorbate Peroxidase Proximity Labeling Coupled with Biochemical Fractionation Identifies Promoters ofRead more
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Protein Linking Key Organelles May Shed Light on Neurodegenerative Disease Development
Sep 26,2017
Poison Frogs Evolved Poison Resistance via Complementary Mutations
Brightly colored but capable of dark deeds, poison frogs accumulate or generate toxic chemicals that are harmful to predators, but tolerable to the frogs themselves. For example, many poison frogs have evolved resistance to their own neurotoxins by swapping out a few amino acids in their neurotransmitter receptors. Some amino acid replacements have altered toxin-bindingRead more
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Poison Frogs Evolved Poison Resistance via Complementary Mutations
Sep 26,2017
Human Dengue Virus Antibodies Protect Mice and Unborn Pups from Zika Virus
    Scientists have discovered that antibodies taken from patients infected with Dengue virus are effective in treating Zika infection in rodents.     The team, led by researchers at Imperial College London and Washington University in St Louis, found that giving Zika-infected mice the antibodies was enough to treat the early stages of infection, and even protected unbornRead more
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Human Dengue Virus Antibodies Protect Mice and Unborn Pups from Zika Virus
Sep 25,2017
Mutations Making CRISPR Hyper-Accurate Discovered
The potential benefits of the CRISPR gene-editing system have been championed by a huge array of researchers, clinicians, and biotech companies. While the data in recent years supports that CRISPR/Cas9 is effective in altering genes to circumvent many disease states, the limitation of the system thus far has been the tendency of the Cas9 enzymeRead more
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Mutations Making CRISPR Hyper-Accurate Discovered
Sep 25,2017
Antibiotic Sensitivity Rapidly Measured Using Crystals and Vibrations
National Institute of Standards and Technology (NIST) scientists employing the use of quartz crystals to sense bacterial vibrations is a phrase one might expect to read in a new age spiritualism magazine, not in a peer-reviewed scientific journal. Yet, the NIST investigators have recently demonstrated a potential new tactic for rapidly determining whether an antibioticRead more
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Antibiotic Sensitivity Rapidly Measured Using Crystals and Vibrations
Sep 22,2017
PTSD Linked with Increased Lupus Risk
Psychoneuroimmunology is the study of the physiological interactions between the nervous system and immune functions within the body. This discipline can trace its origins back to the mid 1800's to ideas that were more superstition than science. However, in recent years, solid scientific data has shown how the brain and various psychological states can greatlyRead more
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PTSD Linked with Increased Lupus Risk
Sep 22,2017
Bio-Inspired Approach to RNA Delivery
By delivering strands of genetic material known as messenger RNA (mRNA) into cells, researchers can induce the cells to produce any protein encoded by the mRNA. This technique holds great potential for administering vaccines or treating diseases such as cancer, but achieving efficient delivery of mRNA has proven challenging. Now, a team of MIT chemicalRead more
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Bio-Inspired Approach to RNA Delivery