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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Nov 06,2017
ELISA Assay Development
Principles The Enzyme-Linked ImmunoSorbent Assay, or ELISA, is a technique used to detect the presence of a specific molecule in a given sample. The molecule to be detected could be an antibody or antigen.Basically, a small plastic well is coated with an antibody that binds to the antigen of interest (for example, a toxin). SampleRead more
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ELISA Assay Development
Nov 03,2017
Microbiome Link with Colorectal Cancer Drug Toxicity Points to Predictive Tests and Prevention
Albert Einstein College of Medicine researchers report that the composition of people's gut bacteria may explain why some of them suffer life-threatening reactions after taking a key drug for treating metastatic colorectal cancer. The findings indicate that it may be possible to use simple gut microbiome sampling tests to predict drug response, but also suggestRead more
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Microbiome Link with Colorectal Cancer Drug Toxicity Points to Predictive Tests and Prevention
Nov 03,2017
Statistical Model Identifies Novel Cancer-Associated Genes
A new statistical model has enabled researchers to pinpoint 27 novel genes thought to prevent cancer from forming, in an analysis of over 2,000 tumors across 12 human cancer types. The findings could help create new cancer treatments that target these genes, and open up other avenues of cancer research. "Using this powerful toolkit, we'veRead more
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Statistical Model Identifies Novel Cancer-Associated Genes
Nov 03,2017
Fluorescence In Situ Hybridization (FISH)
Fluorescence In Situ Hybridization (FISH) FISH is a technique used to identify and localize the presence or absence of specific DNA sequences on cells and tissues.   PrinciplesThe technique can detect target molecules (sequences of DNA or RNA) in single cells.   In general, nucleic acid probes are used to hybridize to whole cell chromosomes. IfRead more
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Fluorescence In Situ Hybridization (FISH)
Nov 02,2017
Soy Protein May Protect Against Breast Cancer, but Possibly Not Heart Disease
The FDA confirmed that is proposing a rule to revoke a previously authorized health claim that soy protein protects against heart disease. "For the first time, we have considered it necessary to propose a rule to revoke a health claim because numerous studies published since the claim was authorized in 1999 have presented inconsistent findingsRead more
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Soy Protein May Protect Against Breast Cancer, but Possibly Not Heart Disease
Nov 02,2017
Pumpkin Genomes Sequenced in Time for Halloween, Revealing Curious Evolution
For some, pumpkins conjure carved Halloween decorations, but for many people around the world, these gourds provide nutrition.  Scientists at the Boyce Thompson Institute (BTI) within Cornell University and the National Engineering Research Center for Vegetables in Beijing have sequenced the genomes of two important pumpkin species, Cucurbita maxima and Cucurbita moschata.   Findings fromRead more
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Nov 01,2017
Pancreatic Cancer Target Identified in Normal Stromal Cells
Cancer of the pancreas is a deadly disease, with a median survival time of less than six months. Only one in 20 people with pancreatic cancer survives five years past the diagnosis. The reason is the cancer's insidiousness; tumor cells hide deep inside the body, betraying no symptoms until late in the disease, when theRead more
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Pancreatic Cancer Target Identified in Normal Stromal Cells
Nov 01,2017
Immune Cell Behavior May, Ironically, Suppress Effectiveness of Immunotherapy
Researchers have uncovered a surprising process within a key immune cell that may help explain the limitations of immunotherapy as a cancer treatment. Regulatory T cells (Treg cells) are known to suppress immune function after T cells finish their job in fighting an infection. Cancer immunotherapy functions by boosting the immune system to attack cancer; thus, whenRead more
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Immune Cell Behavior May, Ironically, Suppress Effectiveness of Immunotherapy
Nov 01,2017
Fluorescent Antibody Technique (Direct, Indirect)
What is Fluorescent Antibody Technique (Direct, Indirect)? Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (fluorescent antibody technique, direct) or an indirect method, by formation of antigen-antibody complex which is then labeled with (fluorescent antibody technique, indirect). Direct Fluorescent Antibody Test PrinciplesFluorescence microscopy requires a special typeRead more
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Fluorescent Antibody Technique (Direct, Indirect)
Oct 31,2017
Novel Lung Cancer Biomarkers Identified
By now, if you aren't aware of the association between smoking and lung cancer, then it is possible you may have just awoken from some Van Winkle-esque spell, as tobacco smoking is the most well-known environmental risk factor associated with lung cancer.   Now, new evidence from investigators at Dartmouth College has cemented the interactionsRead more
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Novel Lung Cancer Biomarkers Identified