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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Nov 09,2017
Stem Cell Restoration of Hearing Loss Might Be a Double-Edged Sword
Stem cells have been a boon to biological research, allowing researchers to visualize and develop potential therapies for diseases where intervention has hit a wall. However, not all stem cell therapies are as simple as adding undifferentiated cells to damaged areas, allowing natural biological processes to take hold.   For instance, inner ear stem cellsRead more
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Nov 09,2017
Cancer Chemotherapy Resistance Stopped By Chromatin Regulation
Researchers at Northwestern University have developed a new approach to treating cancer that effectively changes the physical structure of chromatin and blocks the cell's ability to modify global gene expression patterns and evolve resistance to therapy. The researchers, led by Vadim Backman, Ph.D., the Walter Dill Scott Professor of Biomedical Engineering at Northwestern's McCormick SchoolRead more
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Cancer Chemotherapy Resistance Stopped By Chromatin Regulation
Nov 09,2017
Principles and types of ELISA
The principle of ELISA The basis of ELISA is the immobilization of antigen or antibody and the enzyme labeling of antigen or antibody. The antigen or antibody bound to the surface of the solid phase carrier still maintains its immunological activity, and the enzyme-labeled antigen or antibody retains both its immunological activity and enzyme
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Principles and types of ELISA
Nov 08,2017
Cheating Chromosomes Vault Past Competitors to Reach Egg Cell First
Each of your cells contains two copies of 23 chromosomes, one inherited from your father and one from your mother. Theoretically, when you create a gamete – a sperm or an egg – each copy has a 50-50 shot at being passed on. But the reality isn't so clear cut.   Studies by scientists atRead more
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Nov 08,2017
Liquid Biopsy Improved for Characterization of Metastatic Tumors
The promise of advanced, minimally invasive techniques, such as liquid biopsy, for diagnosing and tracking cancer progression has pushed researchers to develop accurate, scalable approaches for monitoring cancer DNA from blood samples.   Now, investigators at the Broad Institute of MIT and Harvard, Koch Institute at MIT, Dana-Farber Cancer Institute (DFCI), and Massachusetts General HospitalRead more
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Nov 07,2017
Lab-Designed Molecules Offer New Approach to Treating Superbug Infections
A team led by researchers from the Spanish National Research Council (CSIC) has made an important breakthrough in the battle against superbugs and their resistance to multiple drugs. Scientists have designed molecules that can break the cellular mechanisms of bacterial resistance conventional antibiotics. The results of this discovery ("Membrane Microdomain Disassembly Inhibits MRSA Antibiotic Resistance”)Read more
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Lab-Designed Molecules Offer New Approach to Treating Superbug Infections
Nov 07,2017
Tuning the Microbiome Improves Melanoma Immunotherapy Response
Bacteria that live in the human digestive tract can influence how cancer responds to immunotherapy, opening a new avenue for research to improve treatment, a team led by researchers at The University of Texas MD Anderson Cancer Center reports in the journal Science.  Findings from the new study – ("Gut Microbiome Modulates Response to Anti–PD-1Read more
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Tuning the Microbiome Improves Melanoma Immunotherapy Response
Nov 07,2017
Single Cell Western Blot
A new approach to study protein expression on a cell-by-cell basis. Almost all cells studied in vitro and in vivo, including stem cells and cancer cells, do not represent a homogenous population but are inherently heterogeneous at a molecular level. The biological department of Shanghai Medicilon has extensive experience in the field of in vitroRead more
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Single Cell Western Blot
Nov 06,2017
Stem Cell Subset Source of All Blood Cells, Basis of Bone Marrow Transplant Success
A new blood system isn't created from scratch – just something close to it. A single type of stem cell, a new study demonstrates, can fully repopulate the bone marrow and give rise to all the cell lineages that constitute a complete blood system.   This blood-forming stem cell is distinguished by three cell-surface markersRead more
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Nov 06,2017
New DNA Repair Mechanism in Tuberculosis Uncovered
Tuberculosis (TB) remains a significant threat to much of the world's population – affecting up to two billion people annually. It has sat, unwavering, near the top of the list for deadliest diseases. Moreover, current therapeutics to treat the disease is becoming increasingly ineffective as drug resistance continues to rise exponentially.   Now, new researchRead more
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