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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Nov 29,2017
Efficacy and safety evaluation of tocilizumab in adult systemic sclerosis
Systemic sclerosis is a rare disabling autoimmune disease with few treatment options. Recently, Khanna D of the University of Michigan in the United States conducted a phase II randomized double-blind placebo-controlled trial (faSScinate) to evaluate tocilizumab (IL-6 receptor alpha inhibitor) in patients with systemic sclerosis (SSc) In the efficacy and safety. Researchers conducted a double-blind,Read more
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Nov 28,2017
CRISPR Editing Creates TCR Swap-Shop for Cancer Immunotherapy
A team at Cardiff University in the U.K. has used CRISPR/Cas9 genome editing to generate engineered killer T cells that are up to a thousand times more sensitive to cancer cell antigens than T cells engineered using more conventional approaches, and which allowed far better targeting of T cells to cancer cell lines and patient-derivedRead more
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Nov 28,2017
Fat Cells Feel the Burn when Metabolism is Spiced with Cinnamon
If you want to lose weight, you should avoid stuffing yourself with cinnamon rolls and other cinnamon-spiced treats. Yet cinnamon itself isn't the problem. The common holiday spice might actually protect against obesity and hyperglycemia.   Cinnamon contains an essential oil, cinnamaldehyde, helps give the spice its distinctive flavor and has been proven to protect miceRead more
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Nov 27,2017
Metastasizing Cancer Cells Prefer Denser Collagen
Cancer that spreads throughout the body from where it started is called as metastatic cancer and the process is termed as metastasis. This metastatic spread of tumor cells from one location to another in the body is the cause of 90% of cancer-related deaths.   A team of bioengineers and bioinformaticians at the University ofRead more
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Nov 27,2017
New Malaria Species Discovered in Wild Bonobos
Due to its devastating effects on humans, the conversation surrounding malaria infections is often focused on the public health threat – rightfully so, as close to 50% of the world's population live in areas endemic to malaria with over 200 million cases annually and almost half a million deaths. However, the fact that malaria parasitesRead more
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Nov 24,2017
Stroke Relief Ideas from Ground Squirrels Aren't Nuts
When ground squirrels hibernate, they dramatically reduce the flow of blood to their brains. Yet the squirrels suffer no ill effects, thanks to a cellular process called SUMOylation. By burrowing into the SUMOylation secrets hoarded by squirrels, scientists hope to retrieve molecular boons for people who suffer ischemic stroke, which typically results from a bloodRead more
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Stroke Relief Ideas from Ground Squirrels Aren't Nuts
Nov 24,2017
Critical Signaling Protein for Muscle Growth Described
Researchers at the University of Louisville School of Medicine say they have discovered that a well-known protein, myeloid differentiation primary response gene 88 (MyD88), plays a critical role in the development and regeneration of muscles. Ashok Kumar, Ph.D., professor and distinguished university scholar in the department of anatomical sciences and neurobiology, led a team ofRead more
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Critical Signaling Protein for Muscle Growth Described
Nov 23,2017
Happy Thanksgiving 2017
Thanksgiving is the time to say thanks to our valued colleagues and friends. In this time of gratitude, we give thanks for you.  We value your patronage and appreciate your confidence in us. Counting you among our clients is something for which we are especially grateful. Medicilon wish you a very happy, warm and wonderfulRead more
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Happy Thanksgiving 2017
Nov 23,2017
Consistency Evaluation Enters a Critical Period, CRO Leading Pharmaceutical Companies May Benefit
Consistency evaluation is a major favorable policy for the overall improvement of the pharmaceutical industry. The key aspects of general R&D implementation include "reference preparations-secondary development of prescription processes (pharmaceutical research)-BE filing-BE testing-on-site assessment-review by drug control institutes-consistent Application for sexual evaluation-CFDA approval”. At present, it takes about 20-28 months to complete the entire processRead more
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Consistency Evaluation Enters a Critical Period, CRO Leading Pharmaceutical Companies May Benefit
Nov 22,2017
Using Cancer Drugs to Control Blood Pressure
In the fast-paced world of drug discovery, repurposing existing FDA-approved drugs is a logical strategy, as it not only can save time and money but also can ultimately save lives since drugs can get to patients much quicker. It is incumbent upon researchers to explore all potential treatment possibilities for various compounds, even when theyRead more
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Using Cancer Drugs to Control Blood Pressure