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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Dec 11,2017
Diabetics Can Better Monitor Blood Glucose Levels via Novel Smartphone Approach
University of California, San Diego, (UCSD) researchers say they have developed a smartphone case and app that could make it easier for patients to record and track their blood glucose readings, whether they're at home or traveling.   Currently, checking blood sugar levels can be a hassle for people with diabetes, especially when they haveRead more
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Diabetics Can Better Monitor Blood Glucose Levels via Novel Smartphone Approach
Dec 11,2017
Biacore Analysis Service 8K
The Biacore™ 8K is the newest member of the Biacore family of products. Biacore 8K efficiently delivers binding data with the quality you expect while meeting tomorrow's challenges in small molecule and biotherapeutic screening and characterization. Discover more, more efficiently. · Single solution for interaction analysis in both screening and characterization· Screening of 2300 smallRead more
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Biacore Analysis Service 8K
Dec 08,2017
Trace Element in Drinking Water Slows Alzheimer's Death Rate
Researchers at Brock University in Ontario have recently found an interesting correlation between Alzheimer's disease (AD) and drinking water – and no, it doesn't have to do with the government lacing the water with mind-altering compounds. The researchers collected statistics on the levels of lithium in drinking water in 234 counties across the state ofRead more
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Dec 08,2017
Mitochondrial DNA Varies between Mitochondria within Individual Cells
To find better ways of diagnosing and treating mitochondrial diseases, scientists sift through mitochondrial DNA – and they have just started to use a very fine screen. At the University of Pennsylvania, School of Medicine, researchers led by James Eberwine, Ph.D., have developed a means of sequencing the DNA of individual mitochondria. The researchers haveRead more
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Mitochondrial DNA Varies between Mitochondria within Individual Cells
Dec 07,2017
Novel Drug Shows Promising Results in Alzheimer's Model
Scientists report that a novel small-molecule drug, which works by stopping toxic ion flow in the brain that is known to trigger neuronal apoptosis, can restore brain function and memory in a mouse model of Alzheimer's disease (AD). The team believes the drug could be used to treat AD and other neurodegenerative diseases such as Parkinson's andRead more
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Novel Drug Shows Promising Results in Alzheimer's Model
Dec 07,2017
Biomarker Screen Improves Accuracy of Chemical Genotoxicity Testing
An international research team has developed an in vitro transcriptomic biomarker that can predict, with up to 90% accuracy, whether a drug candidate or other chemical compound is likely to cause the type of cellular injury that can lead to cancer. The TGx-DDI biomarker comprises a panel of 64 transcribed genes that reflect cellular stress responseRead more
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Biomarker Screen Improves Accuracy of Chemical Genotoxicity Testing
Dec 07,2017
Ames Assay Test by Medicilon
Ames Test Services The Ames test is an assay that measures bacterial revertant colony formation; it was named to honor Bruce Ames, who first identified and reported the utility of this assay in detecting mutations in 1974 (Ames, 1974). The Ames assay is the most commonly used assay to predict mutagenic potential of a testRead more
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Ames Assay Test by Medicilon
Dec 06,2017
Your Genes Might Blow Your Diet
We are all aware that what we eat can have a major impact on our health, but new research by scientists in the U.S. suggests that our genes may influence which type of "healthy” diet will be best for each one of us. "Dietary advice, whether it comes from the U.S. government or some otherRead more
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Your Genes Might Blow Your Diet
Dec 06,2017
Epigenetic Surgery Can Reactivate Genes without Butchering DNA
If DNA is to go under the knife, the cuts should be made with a scalpel, not a cleaver. For example, DNA bases may need to be relieved of the methyl groups they've accumulated during gene-silencing reactions. Excising the entire methylated base and replacing it with a demethylated base risks damaging the DNA. It appears,Read more
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Dec 06,2017
Biochemical hERG Safety Assay
Cardiotoxicity is one of the major safety concerns in drug discovery, which is the leading reason for development termination and market withdraw or restriction. Particularly, hERG ion channel inhibition or blockade is responsible for 25-40% of all preclinical lead compound discontinuance. Human ether-a-go-go (hERG), a potassium channel that is abundant in the cardiomyocytes, represents oneRead more
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Biochemical hERG Safety Assay