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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Dec 29,2017
Hidden Structural Variations Emerge from Long Reads of a Complex Genome
Genomes assembled from shreds and patches may fail to represent all mutations, which include not only the single-nucleotide variants and small indels so ably detected by standard short-read sequencing methods, but also mutations that add, subtract, rearrange, or otherwise reconfigure genomic structures. Genomes more resplendent may be needed – genomes that are assembled from longRead more
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Dec 28,2017
Team Takes Important Step in Better Understanding Calcific Aortic Valve Disease
The diminutive size of our aortic valve – just shy of a quarter – belies its essential role in pushing oxygen-rich blood from the heart into the aorta, our body's largest vessel, and from there to all other organs. Yet for decades, researchers have focused less on damaged valves than on atherosclerosis, the gradual hardeningRead more
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Dec 28,2017
Five New Genomic Regions Found that Boost Risk of Asthma
Asthma is a chronic inflammatory disesase involving the airway in the lungs that affects more than 300 million people worldwide including 10 to 20 % of children. Symptoms include episodes of wheezing, coughing, chest tightness, and shortness of breath. It has a significant socio-economic impact and characterized by clinical heterogeneity. Asthma results from genetic predisposition and exposure toRead more
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Dec 27,2017
Team Shows How Dicer Protein Detects and Destroys Viral Invaders
When viruses infect the body’s cells, those cells face a difficult problem. How can they destroy viruses without harming themselves?  Researchers at University of Utah Health have discovered a protein that cuts apart the genetic material of harmful invading viruses. Their research shows how the protein detects the intruders and processes them for destruction to protect cellsRead more
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Dec 27,2017
Technique Converts Harmful Autoantibodies into Anti-Inflammatory Antibodies In Vivo
A team of Massachusetts General Hospital (MGH) and Harvard Medical School investigators have found a way to engineer antibodies within an organism, converting autoantibodies that attack "self” tissues into anti-inflammatory antibodies in animal models of two autoimmune diseases. The technology, developed in the laboratory of Robert Anthony, Ph.D., at the Center for Immunology and InflammatoryRead more
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Technique Converts Harmful Autoantibodies into Anti-Inflammatory Antibodies In Vivo
Dec 26,2017
Nanomedicine Technique Advances Effectiveness of Cancer Therapy
Oregon State University (OSU) scientists have developed a nanomedicine platform for cancers that can help doctors know which tissue to cut out as well as kill any malignant cells that can't be surgically removed. The scientists from the OSU/Oregon Health & Science University (OHSU) College of Pharmacy and OSU College of Veterinary Medicine published their study ("A Tumor-ActivatableRead more
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Nanomedicine Technique Advances Effectiveness of Cancer Therapy
Dec 26,2017
Moving a Step Closer to Solving Problems of Autoimmune Disease and Transplant Rejection
Researchers at the Houston Methodist Research Institute report that they have identified a critical switch that controls T-cell function and dysfunction and have discovered a pathway to target it. Their study ("Ablation of Transcription Factor IRF4 Promotes Transplant Acceptance by Driving Allogenic CD4+ T Cell Dysfunction”) appears in Immunity.   According to Wenhao Chen, Ph.D., a scientistRead more
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Moving a Step Closer to Solving Problems of Autoimmune Disease and Transplant Rejection
Dec 26,2017
What is PCR (Polymerase Chain Reaction)?
PCR (Polymerase Chain Reaction) technology is a DNA synthesis amplification technology in vitro. It has the characteristics of high amplification efficiency, high amplification specificity, and simple and mature amplification system and technology. It is the most widely used technology in biology-related laboratories today.
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What is PCR (Polymerase Chain Reaction)?
Dec 22,2017
Arthritis Drug Combined with Anticancer Therapeutic Shows Promise against Melanoma
Researchers say that treatment for the most deadly form of skin cancer could be more effective if combined with a well-known drug for rheumatoid arthritis. Scientists from the University of East Anglia (UEA) in Norwich, England, working with mice, discovered found that the two treatments together almost completely stopped the growth of a melanoma tumor.  Read more
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Dec 22,2017
Knockout Gene Model Has a Nose for Knockout Breath
Halitosis, or chronic bad breath, afflicts both mice and men, and mice may be used to model human halitosis. But scientists don't have to put their noses up to mice's mouths. Just ask the scientists who participated in an international effort to study halitosis at the genetic level. By studying patients from families afflicted withRead more
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Knockout Gene Model Has a Nose for Knockout Breath