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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Jan 12,2018
LC-MS Method Development and Validation
Drug discovery is the process of generating compounds and evaluating all their properties to determine the feasibility of selecting one new chemical entity (NCE) to become a safe and effective drug. Pharmaceutical companies are under ever-increasing pressure from both their business competition and the patient population to increase the rate of drug discovery. (LC) Liquid.
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LC-MS Method Development and Validation
Jan 11,2018
Identical Twins Share Matching Epigenetics
An international group of researchers has discovered a new phenomenon that occurs in identical twins: independent of their identical genes, they share an additional level of molecular similarity that influences their biological characteristics. The researchers propose a mechanism to explain the extra level of similarity and show that it is associated with risk of cancerRead more
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Jan 11,2018
Genetic Influence for Obesity Linked to a Baker's Dozen
The impact that our genetic background has on daily metabolism cannot be overstated, as a team of investigators has just discovered that variations within 13 genes can have a considerable influence on how easily an individual can gain or lose weight. This large-scale genome-wide association study (GWAS), overseen by the Genetic Investigation of Anthropometric TraitsRead more
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Genetic Influence for Obesity Linked to a Baker's Dozen
Jan 11,2018
Flow Cytometry Test Services
The Flow Cytometry department performs a wide variety of testing which includes immunophenotyping of cells used for the diagnosis of leukemia/lymphoma, CD4 counts for persons living with HIV/AIDS, platelet antibodies and platelet reticulocytes.
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Flow Cytometry Test Services
Jan 10,2018
Novel Approach Shows Which Breast Cancer Patients May Develop Incurable Metastases
Scientists from King’s College London, funded by Breast Cancer Now, believe they have found a way to identify lymph-node positive breast cancer patients who are most likely to develop incurable secondary tumours (metastases) and those who are less at risk. They published their study ("Histological Scoring of Immune and Stromal Features in Breast and AxillaryRead more
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Jan 10,2018
Heart Disease Prediction Made Easier with New Polygenic Test
Investigators at Laval University in Quebec have just released data confirming the polygenic contribution of early-onset coronary artery disease (EOCAD). The researchers found that a polygenic risk score – based on multiple genetic differences – predicted significantly more cases of early-onset heart disease than standard tests for single genetic defects.   Findings from the newRead more
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Jan 09,2018
Gut Microbiome Assemblage Impacts Response to Cancer Immunotherapy
University of Chicago Medicine researchers report that specific microbiome assemblages can boost the response rate to immunotherapy for patients being treated for advanced melanoma. Their study (”The Commensal Microbiome Is Associated with Anti–PD-1 Efficacy in Metastatic Melanoma Patients”) is published in Science. "Anti–PD-1–based immunotherapy has had a major impact on cancer treatment but has only benefitedRead more
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Gut Microbiome Assemblage Impacts Response to Cancer Immunotherapy
Jan 09,2018
Taking Paracetamol during Pregnancy May Harm Fertility of Daughters
A review of experimental studies in rodent models suggests that taking paracetamol (acetaminophen, or N-acetyl-para-aminophenol [APAP]) during pregnancy may be harmful to the future fertility of female pups. Dr. David Kristensen and colleagues at Copenhagen University Hospital say their analysis of three published experimental studies in mice and rats indicates that the female offspring ofRead more
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Jan 08,2018
Sleeping Sickness Turns Out to Be Circadian Rhythm Disorder
Researchers from the Instituto de Medicina Molecular report that African sleeping sickness is a circadian rhythm disorder caused by the acceleration of biological clocks controlling a range of vital functions besides sleep. By understanding which clock genes are affected by the parasitic disease, scientists hope the research will eventually prove useful in developing therapeutic alternatives toRead more
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Jan 08,2018
Microbial Metabolite Could Be Potential Weapon against Skin Cancer
There is an old metaphysical concept that suggests for every poison that nature produces, somewhere it also makes the antidote. Investigators at Oregon State University (OSU) may now be able to extrapolate the metaphysics into reality, as they have recently published findings of a new study that describes a soil-dwelling bacterium producing molecules that induceRead more
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Microbial Metabolite Could Be Potential Weapon against Skin Cancer