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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Feb 20,2018
Increased Dementia Risk Linked to Poor Cardiorespiratory Fitness
We all know that slogging to the gym on a regular basis has positive effects on our future well-being. While this sentiment should seemingly be a motivating factor to keep oneself in shape, it tends to do little in the way of inspiring us to get out of bed early on those chilly winter mornings.Read more
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Feb 16,2018
Reprogramming Fibroblasts into New Heart Cells
Creating new healthy heart muscle cells within a patient’s own ailing heart. This is how scientists hope to reverse heart disease one day.  Researchers reported important molecular details that could lead to the development of new heart cells. In a study ("Initiating Events in Direct Cardiomyocyte Reprogramming”) published in Cell Reports, two labs at the University ofRead more
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Feb 16,2018
Alzheimer's Disease Reversed in Mouse Model
With a large swath of the population entering its senior years, the number of Alzheimer's disease (AD) cases is expected to skyrocket, placing a tremendous burden on the healthcare system. Yet, a glimmer of hope may have just emerged as investigators from the Cleveland Clinic Lerner Research Institute (CCLRI) have found that gradually depleting anRead more
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Alzheimer's Disease Reversed in Mouse Model
Feb 15,2018
CRISPR Calls into Question Cancer Drug Target
The self-correcting nature of science has always seemed enigmatic to the uninitiated and armchair scientists. Yet, independent reproducibility is a hallmark of the proper scientific method and essential for validating appropriate therapeutic targets. Now, a team of scientists at Cold Spring Harbor Laboratory (CSHL) has published new evidence challenging previous research that the maternal embryonicRead more
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Feb 15,2018
Stripped Nerves Reinsulated via Epigenetic Modulation
When nerves are damaged by the immune system, they lose some of their myelin, a protective coating that is, for unknown reasons, hard to restore. Myelin repair, a new study indicates, is controlled by an epigenetic mechanism that may be subject to therapeutic control. Potential drugs have even been identified. With further development, these drugsRead more
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Feb 14,2018
Fully Autonomous DNA Nanorobots Target and Starve Tumors in Mice
A team of scientists in the U.S. and China has created programmable DNA origami nanorobots that can seek out and shrink tumors by blocking their blood supply. Tests in mice carrying breast, melanoma, ovarian, and lung tumors showed how the DNA nanorobots homed in on cancer-feeding blood vessels and induced the formation of clots, whichRead more
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Fully Autonomous DNA Nanorobots Target and Starve Tumors in Mice
Feb 14,2018
Novel Algorithm Sheds Light on Cellular Network Structure
Northwestern University researchers say they have developed a new machine-learning algorithm that can help scientists better understand the genetic interactions inside cellular networks. Called "Sliding Window Inference for Network Generation,” or SWING, the algorithm uses time-series data to reveal the underlying structure of cellular networks.   The research ("Windowed Granger causal inference strategy improves discoveryRead more
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Novel Algorithm Sheds Light on Cellular Network Structure
Feb 13,2018
UV Light That Is Safe for Humans but Bad for Bacteria and Viruses
For decades, it’s been known that broad-spectrum UVC light kills viruses and bacteria by destroying the molecular bonds that hold their DNA together. Unfortunately, it also causes skin cancer and cataracts in people. Now, however, scientists have discovered that a narrow spectrum of UVC – known as far-UVC – can eradicate airborne viruses without harmingRead more
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Feb 13,2018
Marketed Antianxiety Drug Reverses Brain Deficits Caused by Alcohol
A drug that is marked in Japan and China to treat anxiety and depression could potentially help the brain to reboot its ability to grow new nerve cells and also reverse psychological problems that can occur during withdrawal from long-term, heavy binge drinking. Studies in a mouse model by researchers at Queensland University of TechnologyRead more
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Feb 12,2018
Low-Asparagine Diet Could Slow Breast Cancer's Spread
To prevent the spread of breast cancer, it may help to limit dietary asparagine, an amino acid found in many foods of animal and plant origin – including, yes, asparagus. But since asparagine may be synthesized in the body, dietary restrictions may need to be accompanied by drugs that interfere with the metabolic pathways thatRead more
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Low-Asparagine Diet Could Slow Breast Cancer's Spread