Pre-clinical evaluation procedure of drug toxicity
Safety of medical nanomaterials
Application of drug toxicology in clinical pharmacy
Application materials for toxicology studies
Pharmacology and Toxicology Studies
Medicilon has a professional team and practical experience in drug safety evaluation, which can provide high-quality data and a fast turnaround period to support various drug safety evaluation studies. Toxicological studies can be performed in accordance with non-GLP or GLP standards. Our research platform has been rated as a Shanghai R&D public service platform.
Medicilon toxicology and pharmacology studies:
Single dose toxicity test (rodent and non-rodent)
Repeated dose toxicity test (rodent and non-rodent)
Safety pharmacological tests: central nervous system research, cardiovascular system (canine and monkey telemetry and non-telemetry technology), respiratory system
Genotoxicity test
Reproductive toxicity test [Fertility and early embryo development toxicity test (reproduction stage I), embryo-fetal development toxicity test (reproduction stage II)]
Immunogenicity test
Toxicokinetics
Local toxicity test (hemolysis, allergy, irritation test)
Service objects: pharmaceutical R&D institutions, pharmaceutical factories, pharmaceutical companies, hospitals, schools, etc.
Preclinical Toxicology Studies
Common toxicology research test items:
Clinical pathological testing items mainly include the following:
Hematology
White blood cell count (total white blood cell count and five counts of white blood cells), red blood cell count, hemoglobin, hematocrit, average red blood cell hemoglobin content, average red blood cell volume, average red blood cell hemoglobin concentration, reticulocyte absolute value and percentage, platelet count, blood cell morphology
Urine analysis
Microscopic examination of volume, specific gravity, pH, color and appearance, protein, glucose, bilirubin, ketone bodies, occult blood, urobilinogen, nitrite, leukocytes, urine sediment
Coagulation
Prothrombin, activated partial thromboplastin time, thrombin time, fibrinogen
Clinical biochemistry
Alkaline phosphatase, total bilirubin, direct bilirubin, indirect bilirubin, alanine aminotransferase, aspartate aminotransferase, γ-glutamyl transferase, urea nitrogen, creatinine, total protein , Albumin, globulin, glucose, total cholesterol, triglycerides, electrolytes (potassium, sodium, chloride), calcium, phosphorus, creatine kinase, high density lipoprotein cholesterol, low density lipoprotein, cholesterol, bicarbonate ( carbon dioxide)
Toxicology studies
Animal facilities and capabilities
Medicilon is fully certified by AAALAC and is a CLP GLP laboratory. The non-clinical safety evaluation of the drug meets the GLP requirements of CFDA, USFDA and OECD. Have the animal facilities and capabilities you need:
Total facility area of 8,000 square meters
Functional area 2,000 square meters
Dog animal room 1,500 square meters: can accommodate 400
Non-human primate room 1,500 square meters: can accommodate up to 400
Rodent barrier system animal house 3,000 square meters: SPF area can accommodate up to 8000; non-SPF area can accommodate 500
Facilities are designed and operated in accordance with international and domestic standards
contact us
Email: marketing@medicilon.com
Phone: 86-021-58591500
Website: www.medicilon.com
The above is about new drug toxicology studies, pre-clinical toxicology studies, if you need service, please contact us.
Acute toxicity test of chemical drugs
General Toxicology Study Service
Pharmacokinetic test / toxicokinetic test
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