LC-MS Analysis Service

LC/MS/MS Method Development & Validation

Development, transfer, and optimization of methods for quantification of drugs in biological matrices 
Quick turnaround time to speed up the drug development process 

Chemical Analytical Center of Medicilon provides general analysis and purification services for the clients. Our experts have rich experience and proficient skills to solve problems, which are highly appreciated by clients.

General Analytical Chemistry Services

– NMR 1D、2D（H-NMR、C-NMR、P-NMR、F-NMR、HSQC、HMBC、COSY、NOESY, et al）
– LC-MS Analysis
– HPLC Analysis (including ELSD)
– Chiral HPLC Analysis

– General LCMS Testing (ROI、LOD、Cl-、SO42-、mp、HM、Specific Rotation、Water Content, et al）

LC/MS Introduction

LC/MS is short for Liquid Chromatography / Mass Spectrometers.

Liquid Chromatography (LC) is a fundamental separation technique in the life sciences and related fields of chemistry. Unlike gas chromatography, which is unsuitable for nonvolatile and thermally fragile molecules, liquid chromatography can safely separate a very wide range of organic compounds, from small-molecule drug metabolites to peptides and proteins.

Mass Spectrometers (MS) also generate three dimensional data. In addition to signal strength, they generate mass spectral data that can provide valuable information about the molecular weight, structure, identity, quantity and purity of a sample.  Mass spectral data add specificity that increases confidence in the results of both qualitative and quantitative analyses.

Why and When to Use LC/MS

The use of LC-MS in many application areas within analytical science continues to grow almost exponentially.  Listed below are some pointers as to applicability of both HPLC as a separative technique and MS as a means of detecting analyte species.

Bioanalytical LC-MS method development for quantitative determination of drugs and their metabolites in biological fluids is crucial during drug development. The need for efficiently generated, regulatory compliant bioanalytical data is reliant on fit-for-purpose methods being developed and validated by experienced LC-MS scientists.

Our bioanalysis LC-MS teams are recognized for the ability to efficiently develop and validate routine and non-routine methods in a wide variety of matrices, and to rapidly employ these assays in a GLP-compliant and high throughput sample analysis environment.

Liquid Chromatography Mass Spectrometry System

Below is part of our current services in the Bioanalytical Department:

– Method Transfer and Optimization (LC-MS/MS and HPLC)
– Method Development and Validation (LC-MS/MS and HPLC)
– High Throughput Analysis to Support Discovery TK/PK/PD Studies
– Analytical Support for Clinical Trials
– Support for Preclinical TK/PK Studies
– Pharmacokinetic (PK) Studies
– Metabolite Identification
– Bioequivalence Studies

Contact Us 

Email : marketing@medicilon.com
Tel : +86 021 58591500

Tips : Above is part of LC/MS analysis service, LC/MS testing price and LC/MS method development . You can also CONTACT US with any question or enquiry you may have. We will be happy to discuss your needs in detail and design an appropriate plan of action.

Related Articles:

LC-MS Method Development and Validation

LC-MS/MS Method Development