Platform Introduction
Shanghai Medicilon chemical analysis and testing platform is a shared platform that provides analysis and testing services.
The platform has a professional and refined scientific research service team. There are more than 80 devices including NMR, SFC, UPCC, ICP-MS, IC, LC-MS/MS, Prep-HPLC, DSC, TGA, etc. The classification registration sample management system is implemented, which implements automatic management and clear charging, and mainly serves the fields of chemistry, medicine, and chemical industry. At present, the platform has established long-term cooperative relations with many companies, providing strong support for the scientific research work of each company.
Cooperation model
(1) Test class
Sign an annual agreement, monthly payment or quarterly payment;
(2) Project category
Sign a single project, you can sign an annual framework agreement.
Undertake business:
(1) Can undertake business-test category:
Serial number
| Instrument/Type
| Instrument model
|
1 |
Nuclear magnetic resonance NMR | Bruker 400 MHz |
2 |
LC-MS | Shimadzu LC-MS 2020 |
Waters UPLC-Qda | ||
Agilent 6120 | ||
3 |
GC-MS | Agilent 7890B; |
Shimadzu GC-MS 2020 | ||
4 |
High performance liquid chromatography HPLC | Agilent 1200； |
Shimadzu 20AD | ||
5 |
Chiral sample analysis UPCC/HPLC | Waters UPCC |
Shimadzu 20AD | ||
6 |
Residual solvent analysis GC-HS | Agilent GC-HS 7890B |
Shimadzu GC-2010 plus | ||
7 |
Ion content analysis IC | Thermo IC 5500 |
8 |
Metal element analysis ICP-MS | PE NexION 1000 |
9 |
UV spectrum UV | PE LAMBDA 365 |
10 |
Infrared spectrum IR | PE Spectrum Two |
11 |
Optical rotation test OR | Anto Paar MCP5300 |
12 |
Differential Thermal Analysis DSC | METTLER DSC 3 |
13 |
Thermogravimetric analysis TGA | METTLER TGA 2 |
14 |
Moisture test KF | METTLER V30S |
| METTLER C30SX | ||
15 |
Ignition residue test ROI | Muffle |
16 |
Loss on drying test LOD | Oven |
| METTLER HX 204 | ||
17 |
Melting point test MP | METTLER MP 70 |
18 |
Solution Clarity Analysis | Clarifier |
19 |
Solubility test | Visual method |
20 |
Microbial limit test | Pharmacopoeia Standard Test |
(2) Can undertake business-analysis projects:
Serial number
| project
| Use the instrument
|
1 |
diQ-NMR | NMR |
2 |
Structural confirmation | NMR |
3 |
Impurity standardization (declaration) | HPLC, GC-HS, moisture meter, ROI |
4 |
API standardization (declaration) | HPLC, GC-HS, moisture analyzer, ROI, titrator |
5 |
Compound main peak preparation | Pre-HPLC |
6 |
Impurity preparation | Pre-HPLC |
7 |
Chiral method screening and splitting | SFC |
8 |
Stability test | Stability box, HPLC, GC-HS and physical and chemical instruments |
9 |
GC-HS methodology development and validation | GC-HS |
10 |
GC-MS methodology development and validation | GC-MS |
11 |
HPLC methodology development and validation | HPLC |
12 |
ICP-MS method development and verification | ICP-MS |
13 |
IC method development and verification | IC |
14 |
LC-MS-MS method development and verification | LC-MS-MS |
15 |
Microbial limit method development and verification | Microbiology laboratory |
(1)
| Nuclear Magnetic Resonance Spectrometer NMR model: |
(2)
| Inductively coupled plasma mass spectrometer ICP-MS model: PE NexION 1000 |
Main function : suitable for the research of metal elements in chemistry, biology, medicine, clinical and so on. It can measure more than 80 elements at the same time, with high sensitivity, simultaneous multi-element rapid analysis, suitable for trace or ultra-trace element analysis of complex systems (10-9~10-12g/L). Such as research techniques for the control and analysis methodology of elemental impurities.
(3)
| Ion Chromatography IC model: Thermofish ICS5000+ (conductivity and amperometric detector) |
Main functions: Widely used in the analysis and methodological studies of anions, cations, organic acids, organic amines, cyanide, sulfur ions, iodide ions, sugars and amino acids in samples from industries such as environment, materials, chemicals, food, biology, and medicine .
(4)
| Triple quadrupole mass spectrometer LC-MS-MS model: Agilent 6410 |
Main functions: suitable for molecular weight determination in chemical, pharmaceutical, chemical and other aspects, detection and methodological study of trace PGI impurities from ppm to ppb levels.
(5)
| Chiral sample analysis model: Waters UPC2/8 column screening |
| model: Shimadzu 20AD/12 column screening |
Main functions:suitable for screening and development of chiral compounds in chemistry, medicine, chemical industry, etc., ee value, chiral purity determination, etc. Provide a powerful method for the resolution of chiral compounds.
(6)
| Chiral split SFC model: SFC80/SFC150 |
Main function: suitable for the resolution of chiral compounds from mg to 100g in chemistry, medicine, chemical industry, etc.
(7)
| Gas chromatography-mass spectrometer GCMS model: Agilent 5977A |
| Model: Shimadzu GC-MS 2020 |
Main function: Suitable for environment, food, petrochemical industry, biomedicine, flavor and fragrance, forensic poison, tobacco and other industries. It can qualitatively and quantitatively detect and analyze small molecular organic compounds with low boiling point and good thermal stability, especially suitable for low boiling point Methodological studies on trace impurities such as potentially genotoxic impurities.
(8)
| Pre-LC model: Waters 2545-QDa150ml/min |
| Preparative chromatography model: Gilson 306 50ml/min |
Main functions: suitable for separation and purification of organic synthesis products of compounds in chemistry, medicine, chemical industry, etc., preparation and separation of trace impurities in raw materials and preparations.
| infrared spectrometer model: PE Spectrum TWO |
| UV spectrometer model: PE Lambda 365 |
| Polarimeter model: Anton Paar MCP5300 |
| Moisture Analyzer: model: METTLER TOLEDO V30S |
| Moisture Analyzer: model: METTLER TOLEDO V30S |
| Potentiometric titrator: model: METTLER TOLEDO T50 |
contact us:
Contact: 021-58591500 or marketing@medicilon.com
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