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- Cytokines are proteins or polypeptides that are secreted by activated immune cells and some stromal cells to mediate and regulate immune and inflammatory responses. Cytokine detection has value in disease diagnosis, basic immune research and cytokine therapy monitoring. We can detect the concentration of cytokines in peripheral blood and also stimulate lymphocytes to secrete cytokines via in vitro culture approaches to amplify the stimulating effect of drugs on immune cells. Using this approach, we can predict the potential risk of drugs that may cause cytokine release syndrome, and determine the minimum expected biological effect level to choose a reasonable and safe starting dose for clinical studies.
- Biomarkers are indicators that can determine the occurrence, development and prognosis of diseases, and play an important role in early diagnosis, disease prevention, drug target confirmation, and drug response. Biomarker detection can provide insight into the mechanism of action or resistance of new drugs in disease models.
- Medicilon can provide cytokine and biomarker detection services for the global drug R&D sector. Medicilon's Bioanalytics Department has the infrastructure and state-of-the-art instruments and equipment, to perform various single or multiplex multi-form cytokine and biomarker detection. Whether it is the early screening of potential candidate cytokines and biomarkers, or the large-scale validation of specific factors and biomarkers, Medicilon's Bioanalytics Department can provide suitable technology platforms and services to meet our clients needs.
Medicilon's Cytokine and Biomarker Detection Technology Platform- Luminex multiplex Assay;MSD multiplex Assay;FACS CBA multiplex Assay;AlphaLISA;Single plex ELISA.
Types of Cytokine Testing Services- Interleukin；IFN（Interferon）; TNF（Tumor necrosis factor）;CSF; TGF; Chemokine; Growth factorWe have accumulated rich experience in cytokine detection and can provide comprehensive index detection services according to our clients' needs.
Service Areas for Cytokine and Biomarker Detection- Tumor Research: Tumor Marker Detection, HPV Detection Vaccine Research Drug Efficacy Evaluation, Drug Development Concentration Detection of Cytokines, Inflammatory Factors, Chemokines, Enzymes Quantitative analysis of phosphorylated proteins and apoptosis-related proteins in cell signaling Autoimmune function analysis Epidemiological Monitor HLA Typing Test Cardiovascular Disease Research Diabetes and Metabolic Disease Research Signal Pathway Research; Gene Mutation Research
Instrument- Bio-Plex 200(Luminex 200); MESO Sector s600; FACS; MD SpectraMax M2/M4/M5; PE EnVision; Gyros
