Join Medicilon at the EUROTOX 2023——57th Congress of the European Societies of Toxicology

We are pleased to announce that Medicilon will exhibit in the EUROTOX 2023 with the Booth #45. The conference starts from September 10-13 at Ljubljana, Slovenia. Medicilon team will be present throughout the conference. Please stop by at our booth and discuss how Medicilon’s services and capabilities could support your research needs and expedite your drug discovery and development process.

About EUROTOX 2023

For the first time ever, the Slovenian Society of Toxicology, will have the honour of hosting a EUROTOX Congress, to which we would like to welcome all toxicologists working in Europe, but also from all over the world. Under the theme “Toxicology – multidisciplinary science leading to safer and sustainable life” the Local Organising Committee, chaired by Dr. Lucija Perharič, and the Scientific Programme Committee (SPC), chaired by Dr. Thomas Weiser, have put together an inspiring programme covering all aspects of modern toxicology. We are particularly keen to emphasise the breadth of toxicology and the importance of interdisciplinary collaboration. Another special feature of EUROTOX 2023 is its hosting city Ljubljana. Ljubljana is an ancient, but young at heart, Central European city with a touch of Mediterranean flair. It is green, picturesque, compact, culturally vibrant and safe.

EUROTOX 2023 will be a congress of friendly distances as the compact city allows participants to quickly move between its historic city center, filled with numerous baroque and Art Nouveau buildings, modern and high-quality hotels, and a long history of culinary excellence resulting in a range of restaurants from traditional to modern at affordable prices, and the congress venue, GR Congress Centre. GR Congress Centre is a spacious venue, offering ample space for the approximately 1,500 expected participants in the plenary and parallel sessions as well as for the poster presentations and exhibition.

Medicilon Toxicology Studies Services

Non-clinical Safety Assessment (GLP & NON-GLP)

Medicilon’s state-of-the-art facilities are fully AAALAC-accredited. With state-of-the-art platforms and experienced scientists, Medicilon ensures that drug efficacy and safety assessments are conducted in the most professional manner while meeting the global regulatory standard. From stand-alone preclinical studies to comprehensive IND-enabling packages, Medicilon provides flexible service options to assist biopharmaceutical clients efficiently reach their development milestones. We boast professional teams and practical experience in drug safety evaluation and can promise high-quality data and fast turnaround time to support various drug safety evaluation. Our toxicology research can be carried out according to non-GLP or GLP standards. Our research platform has been rated as Shanghai R&D Public Service Platform. By the end of 2022, there are already 12 full-set IND projects done in Medicilon (including API, formulation, PD, PK, and safety assessment).

Toxicology studies scope

Non-clinical toxicology services

❖Single and repeated-dose toxicity studies

❖General toxicology

❖Immunogenicity studies

❖Carcinogenicity studies

❖Local toxicity studies (hemolysis, allergy, and irritation tests)

❖Inhalation toxicity studies

❖Toxicokinetic studies

❖ADC safety evaluation

❖Safety pharmacology studies: CNS research, cardiovascular system (telemetry and non-telemetry technology for dogs and monkeys), respiratory system and hERG

❖Reproductive/developmental and juvenile toxicity studies

❖Genotoxicity studies

Histopathology studies

❖H&E staining

❖Immunohistochemistry (IHC)

❖Tissue cross reaction (TCR)

Clinical pathology studies

❖Urinalysis

❖Lymphocyte typing

❖Hematological analysis

❖Hemagglutination analysis

❖Clinical biochemical analysis

Toxicology research service platforms

In addition to common administration routes such as PO and IV, the following characteristic evaluation platforms are also established:

❖The inhalation administration platform

❖Ophthalmic administration platform

❖The skin administration platform

❖Sublingual administration platform

❖The young animal evaluation platform

❖The integrated evaluation technology platform for biological innovative drugs such as antibody, vaccine, ADC and CAR-T cell

Medicilon Inhalation Study Case Studies

Small animal/canine/NHP nose and mouth exposure system

Inhalation delivery methods

Inhalation formulation quality analysis: key equipments

GLP TOX case study: rat and canine mouth and nose exposure

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