Reliable In Vivo Platforms for Neurological Drug Development

CNS Pharmacology Models
evaluate how drug candidates affect the central nervous system, helping to predict therapeutic potential and identify possible side effects early in development.

Why Medicilon’s CNS Pharmacology Models Stand Out

Medicilon’s CNS pharmacology platform provides a comprehensive portfolio of validated in vivo models to support preclinical drug discovery targeting central nervous system (CNS) disorders. From neurodegenerative diseases like Alzheimer’s and Parkinson’s to psychiatric conditions such as depression and anxiety, our models are designed to replicate clinical symptoms, behavioral changes, and treatment response, enabling early and informed decision-making in your drug development pipeline.

Medicilon integrates behavioral analysis, biomarker detection, and histopathological evaluation to deliver translational data with high reproducibility and accelerated timelines.

Multiple Species

Mouse and Rat models adaptable for various CNS indication.

Flexible Study Duration

Acute and Chronic induction protocols.

Standardized Behavioral Paradigms

Reproducible test systems across multiple endpoints.

Biomarker & Histopathology Services

Comprehensive tissue and fluid-based analysis.

High-Quality Data Reports

Actionable, reproducible data to inform go/no-go decisions.

Extensive CNS Disease Models

 

Medicilon offers a diverse selection of CNS Disease Models providing reliable in vivo platforms for your neurological drug development

 

CNS Disease Models:

CNS Disorder
Model Description
Readouts / Tests
FAD 4T Transgenic Mouse
Morris Water Maze, Cognition Wall Test, Pathological Examination
MPTP-Induced Models (Subacute & Chronic) in C57BL/6J Mice
Rotarod, Pole Climb, Grip Strength, Histopathology
Mouse/Rat Behavioral Models
Elevated Plus Maze, Open Field Test, Light-Dark Shuttle
Acute: Tail Suspension & Forced Swim Tests Chronic: CUMS Rat Model
Immobility Time, Sugar Water Preference Test

Accelerate Your CNS Drug Development with Confidence​

Whether you’re optimizing a neuroactive compound, validating a therapeutic mechanism, or seeking proof-of-concept efficacy, Medicilon delivers reliability, scientific depth, and flexibility at every stage.

  • 20 Years of Excellence in preclinical CRO services
  • Expertise in CNS pathophysiology and behavioral neuroscience
  • Rapid Turnaround with complete data support
  • End-to-End Integration from model establishment to IND-enabling studies
Tumor Models
Xenograft Models (186+)
Humanized Models (30+)
Syngeneic Models (30+)
Orthotopic Models (50+)
PDX Models (100+)
Non-tumor Models
CNS Diseases Models (64+)
Inflammatory & Immune Diseases (32+)
Cardiovascular Diseases (25+)
Metabolic Diseases (39+)
Digestive Diseases Models (18+)
cancer therapy INNOVATION

Beyond Orthotopic Models, A Full-Spectrum Oncology Research Suite

Tumor models:

Medicilon provides a comprehensive range of oncology models, including:

  • CDX Models – Fast, reliable tumor models for early-phase drug screening.
  • PDX Models – Clinically relevant models for personalized medicine research.
 

This holistic approach ensures that researchers can seamlessly transition from early drug discovery to translational research, accelerating the path to clinical trials.

 

Commitment to delivering preclinical CNS research, in vivo neurological models

Contact Medicilon

Name
Address

Search Medicilon

Medicilon Supports Moon Biotech’s Groundbreaking MNO-863 Probiotic Drug – Achieves Nearly 10% Weight Loss in 4 Weeks and Secures Dual Clinical Trial Trial Approvals

Zero Defects! Medicilon Supports MeiJi BioPharma’s Oral Paclitaxel Soft Capsule in Gaining FDA IND Approval

Global First! Medicilon Powers Tyercan’s Breakthrough Anti-Tumor Protein-Drug Tye1001 to U.S. and China IND Clearance