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FAQs

What are Polypeptides?

Chemically synthesized, peptides are larger than 40 amino acids but fewer than 100 amino acids (FDA, FDA-2018-N-2732, 2018).
Peptides generally refer to a class of compounds formed by dehydration and condensation of 3-50 A-amino acids.
Compounds usually formed by dehydration and condensation of 10 to 100 amino acid molecules are called polypeptides.
Polypeptides typically refer to peptide chains composed of no more than 50 amino acids, falling within the realm of small-molecule drugs (molecular weight 5000).
A peptide consists of two linked amino acids, whereas a polypeptide, as discussed here, typically contains fewer than 100 amino acids. Many therapeutic peptides consist of between 10 and 100 amino acid molecules.