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Application of PDX Models

New drug development
In particular, patient screening and predictive biomarker studies in clinical trials of tumor immune-targeted drugs show that PDX efficacy evaluation results and clinical similarity reached 87% (CDX only 5%).

Personalized Medicine:
PDX model can be used to conduct pharmacodynamic (PD) evaluation experiments for tumor patients, providing clinical drug references for personalized treatment.

Molecular Marker development (Biomarker)
Drug reactions -- Molecular biological mechanisms